Cold-stored whole blood: A better method of trauma resuscitation?

Background: Cold-stored whole blood (CWB) provides a balance of red blood cells, plasma, and platelets in less anticoagulant volume than standard blood component therapy (BCT). We hypothesize that patients receiving CWB along with BCT have improved survival compared with patients receiving only BCT.

Methods: We performed a dual-center case-match study of trauma patients who received CWB and BCT at two urban, Level-I Trauma Centers.