Publications by authors named "Joshua Narh"

Article Synopsis
  • Familial hypercholesterolaemia (FH) is linked to an increased risk of heart disease, particularly in patients who experience acute myocardial injury (AMI), but detailed outcomes for these patients have been understudied.
  • The research analyzed data from US hospitals between 2018 and 2020, focusing on adults with AMI to compare outcomes based on the presence of FH.
  • Findings revealed that FH patients had higher rates of ST-elevation and non-ST-elevation myocardial infarctions, required more invasive procedures, but exhibited lower all-cause mortality and lower incidences of type 2 MI and takotsubo cardiomyopathy compared to those without FH.
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Article Synopsis
  • - The study investigated the effects of long-term systemic steroid use on complications after ST-segment elevation myocardial infarction (STEMI), using data from over 608,000 hospital admissions between 2018 and 2020.
  • - Although long-term steroid users (0.9% of total cases) showed lower odds of experiencing electrical complications like ventricular tachycardia and shorter hospital stays, there were no significant differences in overall mortality rates or mechanical complications among groups.
  • - The findings suggest that while steroids may help reduce some heart-related electrical issues post-STEMI, they don’t appear to affect long-term survival or the need for invasive procedures, highlighting a need for further research to confirm these results.
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Kugel's artery is defined as a rare anatomical variant of the coronary artery vascular bed consisting of an anastomotic connection between branches of the right coronary artery (RCA) and/or left circumflex artery (LCX). Kugel's artery has been reported to have an incidence of 6% in the general population. The presence of this anastomotic communication may play a pathophysiological role in a patient with a right dominant coronary circulation and an underlying coronary artery disease (CAD) affecting the right coronary system.

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Background: Coronary artery fistula is a relatively rare disorder with an incidence rate of 0.05-0.9%, and the majority of fistulae are detected incidentally.

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In this retrospective study we analyze and compare clinical characteristics and outcomes of patients with and without cancer history who were infected with novel coronavirus disease 19 (COVID-19). Medical records were reviewed and a comparative analysis of 53 cancer and 135 non-cancer patients with COVID-19 were summarized. Results: The median age for COVID-19 patients with and without cancer was 71.

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Background: Although diffuse alveolar damage and respiratory failure are the key features of coronavirus disease 2019 (COVID-19), the involvement of other organs such as the kidney has also been reported. The reports of the incidence of acute kidney injury (AKI) in COVID-19 patients vary widely. In this study, we report our unique experience with AKI in COVID-19 patients in a low socioeconomic and predominantly ethnic minority group and provide its incidence, risk factors, and prognosis to expand the current understanding of this complication.

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Aim: Elevation of hepatic aminotransferases (aspartate aminotransferase [AST]/alanine aminotransferase [ALT]) is commonly noted among COVID-19 patients. It is unclear if they can predict the clinical outcomes among hospitalized COVID-19 patients. We aim to assess if elevations in AST/ALT were associated with poor outcomes in hospitalized COVID-19 patients.

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Paraneoplastic disorders are rare multiorgan diseases associated with hematological malignancies such as chronic lymphocytic leukemia (CLL). Some of these paraneoplasms manifest as cutaneous lesions, appearing as a simple rash, ulcers or skin thickening. The pathogenesis for this process has been described as development of certain autoimmune reactions against cell wall antigens and proteins.

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