Applying a structured innovation process to interventional radiology: a single-center experience.

Purpose: To determine the feasibility and efficacy of applying an established innovation process to an active academic interventional radiology (IR) practice.

Materials And Methods: The Stanford Biodesign Medical Technology Innovation Process was used as the innovation template. Over a 4-month period, seven IR faculty and four IR fellow physicians recorded observations.

Percutaneous transvenous cellular cardiomyoplasty. A novel nonsurgical approach for myocardial cell transplantation.

Objectives: The study evaluated a nonsurgical means of intramyocardial cell introduction using the coronary venous system for direct myocardial access and cell delivery.

Background: Direct myocardial cell repopulation has been proposed as a potential method to treat heart failure.

Methods: We harvested bone marrow from Yorkshire swine (n = 6; 50 to 60 kg), selected culture-flask adherent cells, labeled them with the gene for green fluorescence protein, expanded them in culture, and resuspended them in a collagen hydrogel.