Tomographic deconvolution phase microscopy (TDPM) is a promising approach for 3D quantitative imaging of phase objects such as biological cells and optical fibers. In the present work, the alternating direction method of multipliers (ADMM) is applied to TDPM to shorten its image acquisition and processing times while simultaneously improving its accuracy. ADMM-TDPM is used to optimize the image fidelity by minimizing Gaussian noise and by using total variation regularization with the constraints of nonnegativity and known zeros.
View Article and Find Full Text PDFA novel quantitative phase imaging method is shown to estimate phase accurately over a wide range of length scales using Köhler illumination from an extended incoherent source. The method is based on estimating the longitudinal intensity derivative in the transport-of-intensity equation via convolution with multiple Savitzky-Golay differentiation filters and generalizes methods previously developed for coherent imaging to the practical scenario of partially coherent imaging. The resulting noise and resolution performance are evaluated via numerical simulation and demonstrated experimentally using a blazed transmission grating as well as a single-mode fiber as test objects.
View Article and Find Full Text PDF