Publications by authors named "Joshua Lane"

Medical and surgical care remain a critical feature of disaster preparedness. The evolution of modern warfare introduces elements manifesting as both domestic and foreign terrorism. The fields of disaster and counterterrorism medicine continue to evolve in response to these looming threats.

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The specialties of disaster and counterterrorism medicine have continued to evolve based on the demand for medical responses to these unique and demanding environments. These medical responses are relevant to all medical specialties; however, surgeons play a particularly critical role. This is evidenced from decades of humanitarian and military surgical involvement.

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Article Synopsis
  • - The threat of CBRNe (chemical, biological, radiologic, nuclear, and explosive) terrorist attacks is growing, highlighting the need for quick and effective medical responses which should be incorporated into physician training early on.
  • - A study of 153 U.S. allopathic medical schools revealed that only 15 (9.8%) offered specific education on CBRNe and counter-terrorism medicine, despite post-9/11 legislation advocating for this training to be prioritized.
  • - While current CBRNe medical counter-measures exist, improving educational content in medical schools is essential; all physicians, regardless of specialty, can contribute to responses to such attacks.
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Introduction: Exsanguination is the leading cause of preventable death on the battlefield and in austere environments. Multiple courses have been developed to save lives by stopping hemorrhage. Training for this requires simulation models; however, many models are expensive, preventing the further expansion of this life-saving training.

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Background: Reconstruction of large nasal surgical defects often warrant the use of mucosal flaps to repair the inner lining. This often presents a challenge for surgical reconstruction.

Objective: To describe a unique reconstructive option for the repair of large surgical wounds that necessitate mucosal nasal lining.

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: To examine the spectrum of scleritis in four tertiary institutions across the Asia-Pacific. : Clinical records from 354 patients were reviewed from centers in Australia, Singapore, and India, excluding those with insufficient data ( = 24). : Indian patients presented younger (41.

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Reported here is a laboratory in vitro evolution (LIVE) experiment based on an artificially expanded genetic information system (AEGIS). This experiment delivers the first example of an AEGIS aptamer that binds to an isolated protein target, the first whose structural contact with its target has been outlined and the first to inhibit biologically important activities of its target, the protective antigen from Bacillus anthracis We show how rational design based on secondary structure predictions can also direct the use of AEGIS to improve the stability and binding of the aptamer to its target. The final aptamer has a dissociation constant of ∼35 nM.

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Objective: A core priority of all medical specialties includes information for members regarding inherent priorities and principles. The authors sought to investigate the priority and contribution of various medical specialties to the fields of bioterrorism, terrorism, disaster preparedness, and emergency preparedness.

Design: A mixed study design (quantitative and qualitative) was used to identify pertinent characteristics of various medical specialties.

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Perineural involvement of a cutaneous neoplasm marks an aggressive feature. Tumors with perineural involvement share an increased propensity for local invasion via perineural spread. Formication may be an indicator of perineural involvement by cutaneous neoplasms.

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Trigeminal trophic syndrome is a rare entity characterized by the presence of ala nasi ulceration, trigeminal anesthesia, and paresthesia. It arises secondary to trigeminal nerve injury. Patients with this diagnosis often undergo repeated skin biopsies to rule out suspected nonmelanoma skin cancer due to the clinical appearance.

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