Neutral auditory words immediately followed by painful electric shock may show reduced next-day recollection.

In this study, we investigated the effect of experimentally delivered acute pain on memory. Twenty-five participants participated in experimental sessions on consecutive days. The first session involved a categorization task to encourage memory encoding.

Memory for non-painful auditory items is influenced by whether they are experienced in a context involving painful electrical stimulation.

In this study, we sought to examine the effect of experimentally induced somatic pain on memory. Subjects heard a series of words and made categorization decisions in two different conditions. One condition included painful shocks administered just after presentation of some of the words; the other condition involved no shocks.

Manipulating memory efficacy affects the behavioral and neural profiles of deterministic learning and decision-making.

When making a decision, we have to identify, collect, and evaluate relevant bits of information to ensure an optimal outcome. How we approach a given choice can be influenced by prior experience. Contextual factors and structural elements of these past decisions can cause a shift in how information is encoded and can in turn influence later decision-making.

Neural signatures of experience-based improvements in deterministic decision-making.

Feedback about our choices is a crucial part of how we gather information and learn from our environment. It provides key information about decision experiences that can be used to optimize future choices. However, our understanding of the processes through which feedback translates into improved decision-making is lacking.

Content-specific evidence accumulation in inferior temporal cortex during perceptual decision-making.

During a perceptual decision, neuronal activity can change as a function of time-integrated evidence. Such neurons may serve as decision variables, signaling a choice when activity reaches a boundary. Because the signals occur on a millisecond timescale, translating to human decision-making using functional neuroimaging has been challenging.

The strength of gradually accruing probabilistic evidence modulates brain activity during a categorical decision.

The evolution of neural activity during a perceptual decision is well characterized by the evidence parameter in sequential sampling models. However, it is not known whether accumulating signals in human neuroimaging are related to the integration of evidence. Our aim was to determine whether activity accumulates in a nonperceptual task by identifying brain regions tracking the strength of probabilistic evidence.

Prior probability and feature predictability interactively bias perceptual decisions.

Anticipating a forthcoming sensory experience facilitates perception for expected stimuli but also hinders perception for less likely alternatives. Recent neuroimaging studies suggest that expectation biases arise from feature-level predictions that enhance early sensory representations and facilitate evidence accumulation for contextually probable stimuli while suppressing alternatives. Reasonably then, the extent to which prior knowledge biases subsequent sensory processing should depend on the precision of expectations at the feature level as well as the degree to which expected features match those of an observed stimulus.

High quality but limited quantity perceptual evidence produces neural accumulation in frontal and parietal cortex.

Goal-directed perceptual decisions involve the analysis of sensory inputs, the extraction and accumulation of evidence, and the commitment to a choice. Previous neuroimaging studies of perceptual decision making have identified activity related to accumulation in parietal, inferior temporal, and frontal regions. However, such effects may be related to factors other than the integration of evidence over time, such as changes in the quantity of stimulus input and in attentional demands leading up to a decision.

Effects of task-set adoption on ERP correlates of controlled and automatic recognition memory.

Successful memory retrieval depends not only on memory fidelity but also on the mental preparedness on the part of the subject. ERP studies of recognition memory have identified two topographically distinct ERP components, the FN400 old/new effect and the late posterior component (LPC) old/new effect, commonly associated with familiarity and recollection, respectively. Here we used a task-switching paradigm to examine the extent to which adoption of a retrieval task-set influences FN400 and LPC old/new effects, in light of the presumption that recollection, as a control process, relies on the adoption of a retrieval task-set, but that familiarity-based retrieval does not.