Publications by authors named "Joshua Engle"

Article Synopsis
  • Glomus tumors are usually benign but can be rare and aggressive in some cases, like the one in a 67-year-old woman whose tumor metastasized to her lungs.
  • The patient underwent neoadjuvant radiation followed by immunotherapy with pembrolizumab, leading to significant disease regression and resolution of lung nodules.
  • The case highlights the potential for using radiation and immunotherapy to manage malignant glomus tumors, which are rare and have uncertain treatment protocols.
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Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the leading causes of cancer-related deaths worldwide. Tumor mutational burden (TMB) in a cancer specimen represents the number of mutations within a pre-determined length of genetic material. This value is increasingly investigated as it may correlate with both prognosis and cancer response to developing immunotherapies.

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One of the goals of this systematic review is to provide a meta-analysis-derived mean OEF of healthy volunteers. Another aim of this study is to indicate the OEF ranges of various neurological pathologies. Potential clinical applications of OEF metrics are presented.

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Background: Infection Preventionist to date are experiencing staffing shortages, the purpose of this narrative review is to understand how heath care organizations track staffing and outcome metrics in relation to Infection Preventionists.

Methods: Databases utilized included MEDLINE, PubMed, EMBASE, Web of Science, and Google Scholar.

Results: The initial search included 668 studies.

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Problem: Requirements for experiential education in quality improvement and patient safety (QI/PS) in graduate medical education (GME) have recently expanded. Major challenges to meeting these requirements include a lack of faculty with the needed expertise, paucity of standardized curricular models allowing for skill demonstration, and inconsistent access to data for iterative improvement.

Approach: In October 2017, the authors began development of a centralized QI/PS flipped-classroom simulation-based medical education (SBME) curriculum for GME trainees across multiple disciplines at Oregon Health & Science University (OHSU).

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