Publications by authors named "Joshua Chakranarayan"

Article Synopsis
  • - The study aimed to enhance patient safety in the epilepsy monitoring unit (EMU) by identifying gaps in care and implementing a simulation training program for staff awareness and optimal practices.
  • - Researchers created an EMU safety checklist and reviewed video footage of patient responses to assess compliance, which led to targeted staff training using high-fidelity simulations.
  • - Results showed significant improvements in key safety measures and response times immediately after training, although some performance declined over time during follow-up assessments.
View Article and Find Full Text PDF

Background: Hyperamyloidosis in the brain is known as the earliest neuropathological change and a unique etiological factor in Alzheimer's disease (AD), while progressive neurodegeneration in certain vulnerable brain regions forms the basis of clinical syndromes. It is not clear how early hyperamyloidosis is implicated in progressive neurodegeneration and what factors contribute to the selective brain vulnerability in AD.

Methods: Bioinformatics and experimental neurobiology methods were integrated to identify novel factors involved in the hyperamyloidosis-induced brain vulnerability in AD.

View Article and Find Full Text PDF