Publications by authors named "Joshua Canning"

Article Synopsis
  • The study investigates the rise in pediatric cannabis intoxications as more areas legalize recreational use, looking specifically at severe outcomes in emergency department cases from 2017 to 2020.
  • Researchers found that 38% of the 138 children studied were admitted to intensive care, with polysubstance use and ingestion of cannabis edibles identified as significant predictors of severe outcomes.
  • For children older than 10, polysubstance ingestion was the main risk factor for severe outcomes, while all younger children primarily ingested edibles, highlighting differences in risks based on age.
View Article and Find Full Text PDF

Introduction: While the opioid crisis has claimed the lives of nearly 500,000 in the U.S. over the past two decades, and pediatric cases of opioid intoxications are increasing, only sparse data exist regarding risk factors for severe outcome in children following an opioid intoxication.

View Article and Find Full Text PDF

Introduction: Crotalidae immune F(ab') (Fab2AV) became available in the USA in 2019 for treatment of rattlesnake envenomation. In the clinical trial comparing Fab2AV to crotalidae immune polyvalent fab (FabAV), Fab2AV was associated with less late hemotoxicity. The purpose of this study was to describe outcomes following use of Fab2AV in patients with rattlesnake envenomation in Arizona.

View Article and Find Full Text PDF
Article Synopsis
  • This article is the final installment of a three-part series about treating poisoned patients in the Intensive Care Unit (ICU).
  • It specifically addresses natural toxins, including heavy metals and toxins from plants, mushrooms, insects, and snakes.
  • The first article covered general patient care and lab testing, while the second article categorized and examined specific toxic agents.
View Article and Find Full Text PDF

Acquired methemoglobinemia is a common, potentially fatal syndrome that can occur as a result of exposure to numerous xenobiotics. A case report of a 14-month-old female who developed methemoglobinemia following a dapsone ingestion. The child was treated with numerous boluses of methylene blue and ultimately required a continuous infusion of methylene blue.

View Article and Find Full Text PDF