Study of the Effects of Remote Heavy Group Vibrations on the Temperature Dependence of Hydride Kinetic Isotope Effects of the NADH/NAD Model Reactions.

It has recently been observed that the temperature()-dependence of KIEs in H-tunneling reactions, characterized by isotopic activation energy difference (Δ = - ), is correlated to the rigidity of the tunneling ready states (TRSs) in enzymes. A more rigid system with narrowly distributed H-donor-acceptor distances (DADs) at the TRSs gives rise to a weaker -dependence of KIEs (i.e.

Asthma control in normal weight and overweight/obese asthmatic children following adenotonsillectomy.

Objectives: Childhood adenotonsillar hypertrophy (ATH) with sleep-disordered breathing (SDB) frequently occurs concomitant with asthma. Adenotonsillectomy and reduction in asthma severity association has been reported. We describe changes in asthma control in nonobese or normal weight and obese/overweight children undergoing adenotonsillectomy for SDB.

Can Bodybuilding Peak Week Manipulations Favorably Affect Muscle Size, Subcutaneous Thickness, and Related Body Composition Variables? A Case Study.

Background: The purpose of this case study was to implement an evidence-based dietary approach to peaking for a bodybuilding competition and monitor its impact on body composition, muscle thickness (MT), intra-to-extra-cellular fluid shifts, subcutaneous thickness (ST), and hydration status. Secondarily, to document any adverse events of this peak week approach in a small, controlled setting. Methods Dietary practices were recorded, and laboratory testing was conducted throughout peak week, including competition morning.

Progressive Resistance Training Volume: Effects on Muscle Thickness, Mass, and Strength Adaptations in Resistance-Trained Individuals.

Aube, D, Wadhi, T, Rauch, J, Anand, A, Barakat, C, Pearson, J, Bradshaw, J, Zazzo, S, Ugrinowitsch, C, and De Souza, EO. Progressive resistance training volume: effects on muscle thickness, mass, and strength adaptations in resistance-trained individuals. J Strength Cond Res 36(3): 600-607, 2022-This study investigated the effects of 12-SET, 18-SET, and 24-SET lower-body weekly sets on muscle strength and mass accretion.

Kinetics of the hydride reduction of an NAD(+) analogue by isopropyl alcohol in aqueous and acetonitrile solutions: solvent effects, deuterium isotope effects, and mechanism.

The rate constants of the hydride-transfer reactions from isopropyl alcohol (i-PrOH) to an NAD(+) model, 9-phenylxanthylium ion (PhXn(+)), in acetonitrile (AN) and in water containing AN (80% H(2)O/20% AN) were determined over a temperature range from 36 to 67 degrees C. The reactions follow second-order rate laws. In the latter solution, formation of the water adduct of PhXn(+) was observed as a side-equilibrium (K).