Publications by authors named "Joshua Balog"

Article Synopsis
  • There is limited data comparing irrigated catheters to non-irrigated catheters for ablating accessory pathways in adults; this study analyzes 69 cases from 2010 to 2017.
  • The study involved mostly middle-aged male patients, with a majority of the accessory pathways located on the left side and a significant number being concealed.
  • Results showed a higher success rate for irrigated catheters (94.4%) compared to non-irrigated ones (73.3%), indicating that irrigated catheters are more effective in ablation procedures.
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Background: Patients with heart failure (HF) develop metabolic derangements including increased adipokine levels, insulin resistance, inflammation and progressive catabolism. It is not known whether metabolic dysfunction and adipocyte activation worsen in the setting of acute clinical decompensation, or conversely, improve with clinical recovery.

Methods And Results: We assessed insulin resistance using homeostasis model assessment of insulin resistance (HOMA-IR), and measured plasma levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP), adiponectin, visfatin, resistin, leptin, and tumor necrosis factor (TNF) α in 44 patients with acute decompensated HF (ADHF) due to left ventricular (LV) systolic dysfunction and again early (<1 wk) and late (> 6 mo) after clinical recovery, in 26 patients with chronic stable HF, and in 21 patients without HF.

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Background: Increased myocyte loss and extracellular matrix (ECM) turnover are central mechanisms that contribute to pathological myocardial remodeling in chronic heart failure (HF). We tested the hypothesis that episodes of acute HF syndrome (AHFS) are associated with transient increases in markers of myocyte injury and ECM turnover beyond those observed in chronic stable HF.

Methods And Results: Markers of myocyte injury and ECM turnover were assessed in 80 patients prospectively divided into 3 groups: AHFS (n=39); chronic stable systolic HF (n=21); and control subjects without HF (n=20).

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