The Efficacy of Combined Decompression of Carpal and Cubital Tunnel in the Setting of Cervical Spine Stenosis: A Retrospective Analysis.

Background and objective Hand numbness, often associated with carpal tunnel syndrome (CTS) and cubital tunnel syndrome (CuTS), significantly impacts the quality of life. This study aimed to evaluate the effectiveness of combined carpal and cubital tunnel decompression (CCTD) in patients with concurrent mild to moderate cervical spine stenosis when compared to single decompression procedures. Methods We retrospectively reviewed the records of 100 patients who underwent decompression surgery for hand numbness and concurrent cervical spine stenosis, with positive electromyography (EMG) results in some cases, between January 1, 2023, and January 1, 2024.

Using Pre-Clinical Studies to Explore the Potential Clinical Uses of Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem cells.

Recent studies of exosomes derived from mesenchymal stem cells (MSCs) have indicated high potential clinical applications in many diseases. However, the limited source of MSCs impedes their clinical research and application. Most recently, induced pluripotent stem cells (iPSCs) have become a promising source of MSCs.

Unexplained chest pain in a patient with giant cell arteritis? Think aortic dissection.

Giant cell arteritis (GCA) is the commonest of the large-vessel vasculitides. Aortic inflammation in patients with GCA was first described over 80 years ago, but it has only been possible to study this systematically following the development of more sophisticated imaging techniques such as computed tomography angiography, magnetic resonance angiography and positron emission tomography. Both NICE and the European League Against Rheumatism (EULAR) recognise that aortic dissection may complicate GCA but stop short of recommending routine imaging.