Veterinary training programs rely on animal cadavers for a variety of important educational activities, yet ethical sourcing can present considerable challenges. Public sentiment has rendered traditional sources (e.g.
View Article and Find Full Text PDF3'-deoxy-3'-[ F]fluorothymidine ( FLT) is a radiopharmaceutical tracer used with positron emission tomography (PET), often in combination with computed tomography (CT), to image DNA synthesis, and thus, cellular proliferation. Characteristic accumulation of the tracer within haematopoietic bone marrow provides a noninvasive means to assess marrow activity and distribution throughout the living animal. The present study utilizes three-dimensional analysis of FLT-PET/CT scans to quantify the relative skeletal distribution of active marrow by anatomic site in the dog.
View Article and Find Full Text PDFPositron emission tomography/computed tomography (PET/CT) utilizing 3'-deoxy-3'-[(18) F]fluorothymidine ((18) FLT), a proliferation tracer, has been found to be a useful tool for characterizing neoplastic diseases and bone marrow function in humans. As PET and PET/CT imaging become increasingly available in veterinary medicine, knowledge of radiopharmaceutical biodistribution in veterinary species is needed for lesion interpretation in the clinical setting. The purpose of this study was to describe the normal biodistribution of (18) FLT in adult domestic cats.
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