A rare vulvar manifestation of neurofibromatosis 1 in a teen.

Neurofibromatosis 1 is an autosomal dominant disorder with cutaneous findings that include multiple café-au-lait spots, axillary/inguinal freckling, dermal, and plexiform neurofibromas. Skin manifestations, including involvement of the vulva, are often the most troubling physical finding to patients. Hormonal and growth factor changes during puberty have been implicated in neurofibroma growth.

OEIS complex associated with chromosome 1p36 deletion: a case report and review.

OEIS complex (Omphalocele, Exstrophy of the cloaca, Imperforate anus, and Spine abnormalities) is a rare defect with estimated incidence of 1 in 200,000 live births. Most cases are sporadic, with no obvious cause. However, it has been rarely reported in patients with family members having similar malformations or with chromosomal anomalies.

Successful pregnancy rates achieved with day 4 embryo transfers.

Objective: To assess the success of day 4 embryo transfers (ETs) following IVF at one institution.

Design: Retrospective analysis.

Setting: A university hospital IVF program.

Predictors of embryo fragmentation and outcome after fragment removal in in vitro fertilization.

Objective: To assess predictors of embryo fragmentation in IVF as well as to compare cycle outcomes between low-grade embryos subjected to defragmentation and high-grade embryos not undergoing defragmentation.

Design: A retrospective, case-control trial.

Setting: A university hospital IVF program.