Long-term efficacy and safety of endoscopic resection for patients with mucosal adenocarcinoma of the esophagus.

Background & Aims: Barrett's esophagus-associated high-grade dysplasia is commonly treated by endoscopy. However, most guidelines offer no recommendations for endoscopic treatment of mucosal adenocarcinoma of the esophagus (mAC). We investigated the efficacy and safety of endoscopic resection in a large series of patients with mAC.

Curative endoscopic resection of early esophageal adenocarcinomas (Barrett's cancer).

Background: In view of the increasing incidence of adenocarcinoma in Barrett's esophagus and the mortality and high morbidity rates associated with surgical therapy for this condition, safe and effective but less invasive methods of treatment are needed.

Objective: To evaluate efficacy and safety of endoscopic resection in these patients.

Design: Single-center prospective study.