Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and co-infected patients: a randomised controlled trial.

It has been hypothesised that co-infection exacerbates HIV progression, and hence anthelminthic intervention in co-infected individuals will delay it. We evaluated effects of high-intensity versus low-intensity praziquantel treatment of schistosomiasis on HIV disease progression among co-infected patients from fishing populations around Lake Victoria, Uganda. : Between August 2012 and September 2015, we conducted an open-label randomised, controlled trial.