Publications by authors named "Josephine Lunaria Berboso"
J Cereb Blood Flow Metab
September 2024
Article Synopsis
- A study involving 272 memory clinic participants aimed to explore the relationship between stiffness in aortic and carotid arteries and various aspects of cerebrovascular disease, cognition, and dementia subtypes.
- Researchers used applanation tonometry and carotid ultrasonography to measure artery stiffness and assessed cognitive function through tests like MMSE and MoCA.
- Results indicated that carotid artery stiffness was significantly linked to markers of cerebrovascular disease and cognitive impairment, showing a stronger impact than aortic stiffness on these health issues.
J Am Heart Assoc
December 2022
Article Synopsis
- Carotid artery stiffness is linked to cognitive impairment and dementia, with a study involving 272 participants using advanced imaging and assessments revealing significant associations between carotid stiffness and various markers of cerebral small-vessel disease.
- Specific metrics of carotid stiffness (like β-index and pulse-wave velocity) were found to correlate with increased white matter hyperintensities and lacunes, indicating potential brain damage linked to vascular changes.
- Though the associations were strong, adjusting for small-vessel disease markers diminished the significance, suggesting that cerebral small-vessel damage may mediate the relationship between carotid stiffness and cognitive decline.
