Publications by authors named "Josephine Lam"

Article Synopsis
  • The study examined the presence and concentration of uric acid (UA) in carotid plaques from patients undergoing carotid endarterectomy, focusing on differences between symptomatic and asymptomatic plaques.
  • Findings revealed that UA was significantly more common and present at higher levels in symptomatic plaques, suggesting a link between UA concentration and cerebrovascular symptoms like stroke.
  • The research indicates that UA could act as both a marker for inflammation in atherosclerosis and a potential contributor to plaque instability, shedding light on its role in the development of cerebrovascular events.
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We describe a modified fulcrum design to overcome limitations of a traditional fulcrum. The modified fulcrum is a triangular prism-shaped foam with rounded and padded edges. The 3 faces of the fulcrum represent 3 different heights (17.

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Germ cell tumor development in humans has been proposed to be part of testicular dysgenesis syndrome (TDS), which manifests as undescended testes, sterility, hypospadias, and, in extreme cases, as germ cell tumors. Males of the Ter mouse strain show interesting parallels to TDS because they either lack germ cells and are sterile or develop testicular germ cell tumors. We found that these defects in Ter mice are due to mutational inactivation of the Dead-end (Dnd1) gene.

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