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Publications by authors named "Josephine Issacov"

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Heparanase expression in Langerhans cell histiocytosis.
Rina Dvir Israel Vlodavsky Neta Ilan Menachem Bitan Josephine Issacov

Pediatr Blood Cancer

October 2014

Heparanase is an endo-beta D-glucuronidase capable of cleaving heparan sulfate side chains, yielding heparan sulfate fragments. Heparanase activity has been correlated with the metastatic potential of tumor-derived cells, angiogenesis, autoimmunity and inflammation. We performed a study of heparanase expression in specimens obtained from patients with Langerhans cell histiocytosis (LCH).

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