Paper-based nuclease protection assay with on-chip sample pretreatment for point-of-need nucleic acid detection.

Pathogen detection is crucial for human, animal, and environmental health; crop protection; and biosafety. Current culture-based methods have long turnaround times and lack sensitivity. Nucleic acid amplification tests offer high specificity and sensitivity.

Disposable glassy carbon stencil printed electrodes for trace detection of cadmium and lead.

Cadmium (Cd) and lead (Pb) pollution is a significant environmental and human health concern, and methods to detect Cd and Pb on site are valuable. Stencil-printed carbon electrodes (SPCEs) are an attractive electrode material for point-of-care (POC) applications due to their low cost, ease of fabrication, disposability and portability. At present, SPCEs are exclusively formulated from graphitic carbon powder and conductive carbon ink.

Quantitative colorimetric paper analytical devices based on radial distance measurements for aqueous metal determination.

Here we report a new microfluidic paper-based analytical device (mPAD) for quantifying metals in water. Metals represent an important class of water contaminants that come from a variety of sources including mining, transportation, manufacturing, waste management, and energy production. Current technologies for quantifying aquatic metals in water are expensive, relatively slow, tedious, provide inadequate performance, and are difficult to use in a field setting.