African American race does not confer an increased risk of clinical events in patients with primary sclerosing cholangitis.

Background: The natural history of primary sclerosing cholangitis (PSC) among African Americans (AA) is not well understood.

Methods: Transplant-free survival and hepatic decompensation-free survival were assessed using a retrospective research registry from 16 centers throughout North America. Patients with PSC alive without liver transplantation after 2008 were included.

Interobserver agreement and prognostic value of image-based scoring systems in patients with primary sclerosing cholangitis.

Background: Primary sclerosing cholangitis (PSC) is a cholestatic liver disease that progresses to cirrhosis and liver failure. The Anali and Amsterdam scores are based upon imaging features on MRI and ERCP, respectively.

Aims: We aimed to compare the interobserver variability and performances of these scores.