Publications by authors named "Joseph Wolfgang Mathews"

Article Synopsis
  • * A case presented involved a patient with hypertension, hyperlipidemia, and type II diabetes, whose adrenal adenoma was discovered due to progressive hirsutism and was found to cause Cushing syndrome.
  • * After surgical removal of the tumor, the patient's symptoms improved significantly, allowing a reduction in medications, and histopathological analysis revealed the adrenal adenoma featured rare lipomatous metaplasia and uncertain malignant potential.
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Ossifying fibromas of the maxillofacial bones are an uncommon form of benign neoplasm usually treated by surgical excision. Up to 30% of patients with hyperparathyroidism-jaw tumor syndrome, a rare form of multiple endocrine neoplasia resulting from autosomal dominant inactivating mutation of the Hrpt2 tumor suppressor gene, initially present with ossifying fibromas. Coincident hypercalcemia because of the presence of parathyroid adenoma is common in these patients, of whom 15% may have or may develop parathyroid carcinoma.

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