Pain Influences Neuropsychological Performance Following Electrical Injury: A Cross-Sectional Study.

Objective: Electrical injury (EI) is a significant, multifaceted trauma often with multi-domain cognitive sequelae, even when the expected current path does not pass through the brain. Chronic pain (CP) research suggests pain may affect cognition directly and indirectly by influencing emotional distress which then impacts cognitive functioning. As chronic pain may be critical to understanding EI-related cognitive difficulties, the aims of the current study were: examine the direct and indirect effects of pain on cognition following EI and compare the relationship between pain and cognition in EI and CP populations.

Establishing the base rate of performance invalidity in a clinical electrical injury sample: Implications for neuropsychological test performance.

: The base rate of neuropsychological performance invalidity in electrical injury, a clinically-distinct and frequently compensation-seeking population, is not well established. This study determined the base rate of performance invalidity in a large electrical injury sample, and examined patient characteristics, injury parameters, and neuropsychological test performance based on validity status.: This cross-sectional study included data from 101 patients with electrical injury consecutively referred for post-acute neuropsychological evaluation.

The relationship between neuropsychological dispersion, processing speed and memory after electrical injury.

: Previous studies of neuropsychological performance in electrical injury (EI) patients have produced evidence of deficits in various cognitive domains, but studies have yet to investigate relationships among performance in cognitive domains post-EI. This study examined whether dispersion among neuropsychological test scores was associated with injury parameters and neuropsychological performance in EI patients. Additionally, we examined whether dispersion, processing speed and/or executive abilities explain variance in episodic verbal and visual memory performance among EI patients.

Examination of the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) validity and substantive scales in patients with electrical injury.

Electrical injury (EI) is a distinct subtype of traumatic injury that often results in a unique constellation of cognitive sequelae and unusual sensory experiences due to peripheral nervous system injury that are uncommon in general medical/neurological populations and have been unexplored with the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF). This study examined performance patterns on MMPI-2-RF validity and substantive scales among 62 EI patients who underwent neuropsychological evaluation, of which 46 demonstrated valid symptom reporting neurocognitive test performance via multiple independent validity indicators and were retained for analysis. Valid EI patients scored significantly higher than the MMPI-2-RF normative sample on several validity scales with the largest effect sizes on F-r (Infrequent Responses), Fs (Infrequent Somatic Responses), FBS-r (Symptom Validity), and RBS (Response Bias), and ≥33% obtaining elevated scores on these scales per standard interpretive criteria.

Psychiatric Outcome Over a Decade After Electrical Injury: Depression as a Predictor of Long-Term Adjustment.

Electrical injury (EI) produces a variety of physical, cognitive, and emotional consequences. Psychiatric and neurocognitive symptoms may complicate survivors' psychosocial adjustment and ability to return to work. However, due to a paucity of longitudinal research, the long-term course of EI remains poorly understood.

Mood and cognition after electrical injury: a follow-up study.

Individuals who have experienced an electrical injury have been reported to demonstrate both acute and delayed cognitive and psychiatric symptoms. The present study assessed 20 electrically injured patients who underwent neuropsychological evaluations twice following their injury. Time since injury, time between assessments, and longitudinal mood changes were evaluated for their potential impact on simple and complex attention outcomes.

Psychiatric morbidity following electrical injury and its effects on cognitive functioning.

Objective: This study examines the prevalence of psychiatric morbidity in a large sample of electrical injury (EI) patients in three phases of recovery and its effects on cognitive functioning.

Methods: Eight-six self-referred EI patients received psychiatric and neuropsychological evaluations. Descriptive statistics were conducted to examine the prevalence of psychiatric morbidity.

Alteration in functional brain systems after electrical injury.

Neuropsychological studies in electrical injury patients have reported deficits in attention, learning, and working memory, but the neural substrates of these deficits remain poorly characterized. In this study we sought to examine whether electrical injury subjects demonstrate abnormal patterns of brain activation during working memory and procedural learning tasks. Fourteen electrical injury subjects and fifteen demographically matched healthy control subjects performed a spatial working memory paradigm and a procedural learning paradigm during functional MRI studies.

Neuropsychological changes following electrical injury.

The clinical presentation of electrical injury commonly involves physical, cognitive, and emotional complaints. Neuropsychological studies, including case reports, have indicated that electrical injury (EI) survivors may experience a broad range of impaired neuropsychological functions, although this has not been clarified through controlled investigation. In this study, we describe the neuropsychological test findings in a series of 29 EI patients carefully screened and matched to a group of 29 demographically similar healthy electricians.

Neuropsychologic functioning and health status in systemic lupus erythematosus: does ethnicity matter?

Background: Despite increased severity of lupus in blacks, including more frequent neuropsychiatric manifestations, there is sparse data on neuropsychologic function in black patients with lupus.

Methods: Neuropsychologic functioning and health-related variables were examined among blacks (n = 34) and whites (n = 14) fulfilling American College of Rheumatology criteria for systemic lupus erythematosus.

Results: Blacks and whites performed comparably on measures of verbal and visual memory, working memory, and motor speed after controlling for estimates of premorbid cognitive ability.