Mixed reality technology for older adults: Evaluating the impact of a novel virtual humanoid coach in a community-based physical exercise program in the Philippines.

Physical inactivity among older adults remains a global burden, leading to a variety of health challenges and even mortality. This study evaluated the impact of a novel virtual humanoid coach-driven physical exercise program among older adults. A non-randomized (quasi) experimental research was conducted in two community senior centers.

Understanding healthcare providers' electronic health record (EHR) interface preferences via conjoint analysis.

Objective: The emergence of Electronic Health Records (EHRs) has been beneficial in processing administrative and clinical data for quality healthcare information. Despite being patient-centered, a number of these technologies have a fractional consideration of the human-computer interaction, which affects the healthcare professionals as end-users. This attempted to surface the healthcare providers' preferences of an ideal EHR system interface in the community setting.

Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor.

Perineural invasion of cancer cells (CPNI) is found in most patients with pancreatic adenocarcinomas (PDA), prostate, or head and neck cancers. These patients undergo palliative rather than curative treatment due to dissemination of cancer along nerves, well beyond the extent of any local invasion. Although CPNI is a common source of distant tumor spread and a cause of significant morbidity, its exact mechanism is undefined.