Publications by authors named "Joseph Thierry Ndongo"
Article Synopsis
- - Sorindeia nitidula is traditionally used for treating influenza symptoms, including headaches and fever, but its active compounds haven't been fully studied yet.
- - The study focused on evaluating the antioxidant, anti-HIV, and antitrypanosomal activities of its ethyl acetate extract, discovering 21 phenolic compounds with notable effects (e.g., potent antioxidant activity at 0.0129 mg/mL).
- - Notably, the extract showed no cytotoxic effects on HeLa cancer cells and leveraged advanced MS techniques to enhance understanding of its beneficial ingredients for potential therapeutic use.
The aim of this study was to identify bioactive secondary metabolites from with potential inhibitory effects against HIV and phytochemical study of root barks resulted in the identification of three new biflavonoids (-), along with four known ones (-). Compound (Gerontoisoflavone A) was a single flavonoid present in the rootbark of the plant and was used as a reference. Compound (IC = 0.
View Article and Find Full Text PDFTwo bisindoline alkaloids, contortarine A, 16-epi-pleiomutinine and a reaction product of pleiomutinine, namely N-chloromethyl-pleiomutinine, were isolated from the roots of Tabernaemontana contorta Stapf. together with five known compounds: pleiomutinine, 1-carbomethoxy-β-carboline, strictosidine lactam, pleiocarpamine, and pleiocarpine. The structures and relative configuration of these alkaloids were determined by extensive 1D and 2D NMR, and MS measurements.
View Article and Find Full Text PDFTwo new flavone glycosides, 3″-O-acetyl-7-O-methylvitexin (1) and 6″-α-rhamnopyranosyl-7-O-methylvitexin (2), along with nine known compounds (3-11) were isolated from the leaves of Rhabdophyllum arnoldianum (Ochnaceae). The structures of the new compounds were established by detailed spectroscopic studies and mass spectrometry, while known compounds were characterised by direct comparison of their reported NMR data with those found in the literature. All these compounds were the first reported from Rhabdophyllum genus.
View Article and Find Full Text PDFFrom the leaves and stem bark of Campylospermum flavum (Ochnaceae), three compounds, namely 4‴-O-methylagathisflavone, flavumchalcone, and flavumindole have been isolated together with 10 known compounds, including three flavonoids, two biflavonoids, two alkaloids, two nitrile glucosides, and glucopyranosyl-β-sistosterol. The structures of these compounds and their relative configurations were established by 1D and 2D NMR experiments. The methanolic crude extracts of leaves and stem bark of C.
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