Publications by authors named "Joseph Soka"
Background: Sickle cell anemia (SCA) prevalence remains high in sub-Saharan Africa. Long-term treatment with hydroxyurea (HU) increases survival, however, poor adherence to treatment could limit effectiveness. Whilst HU treatment adherence is currently high, this might decrease over time.
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- African giant pouched rats, trained by APOPO, effectively detected tuberculosis (TB) in patients, leading to significant findings about their detection capabilities compared to traditional methods.
- In a study of 35,766 patients, rats identified 2,029 cases of TB that would have been missed, representing 52% of total TB diagnoses, especially excelling among patients with low bacillary loads and children.
- The rats were found to be six times more effective than DOT facilities at detecting TB, particularly in children, and showed superior performance in identifying cases with low levels of the Mycobacterium bacilli.