Publications by authors named "Joseph Schwab"

Background Long-term follow-up data are difficult to collect, especially in uncommon foot injuries. Therefore, it is rare to find publications that include patient-reported outcomes. Therefore, a case series and systematic review are provided to evaluate mid- and long-term outcomes.

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Mechanical failure of medical implants, especially in orthopedic poses a significant burden to the patients and healthcare system. The majority of the implant failures are diagnosed at very late stages and are of mechanical causes. This makes the diagnosis and screening of implant failure very challenging.

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Introduction: The Gibson approach, used in hip-preserving surgery, is intermuscular and develops the space anteriorly to the gluteus maximus. Reliable anatomical landmarks for the development of this interval do not exist, but the interval is marked by perforating vessels (PV) of the inferior gluteal artery. The aim of this study was to provide reference values for the relationship between palpable anatomical landmarks on the femur/pelvis and the anterior border of the gluteus maximus using CT scans of the proximal femur.

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Purpose: In modern anterior cruciate ligament (ACL) surgery, the focus is usually on anatomical reconstruction to restore the natural kinematics of the knee. The individual optimal positioning of the ACL footprints (FPs) in primary surgery is still controversial and, especially in revision surgery, difficult to realize surgically. In this regard, a new MRI-based sequence, the Compressed Lateral and anteroposterior Anatomic Systematic Sequence (CLASS) with marked femoral and tibial FPs as a template, could help.

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Purpose: The SORG-MLA was developed to predict 90-day and 1-year postoperative survival in patients with spinal metastatic disease who underwent surgery between 2000 and 2016. Due to the constant changes in treatment methods, it is essential to perform temporal validation with a recent patient population. Therefore, the purpose of this study was to validate the Skeletal Oncology Research Group machine learning algorithms (SORG-MLA) using a contemporary patient cohort.

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Background: Demand for total hip arthroplasty (THA) in ambulatory surgery centers (ASCs) is rapidly increasing. Increased efficiency is crucial in ASCs to manage this rising demand, particularly considering different surgical approaches and their varying time requirements. Optimizing efficiency can help meet the demand while ensuring safe and timely same-day discharge (SDD).

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In 1992, the American Orthopaedic Association-Japanese Orthopaedic Association (AOA-JOA) Traveling Fellowship was created to develop and enhance collaboration between the Japanese and American orthopaedic communities. The fellowship is geared to early-career surgeons and fosters clinical and cultural exchange between members of the 2 countries. In 2024, the fellows hailed from around the United States: Kelly K.

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Introduction: Malleolar fractures are the most common ankle fractures and a major risk factor for ankle osteoarthritis in the long-term. Little is known about modifiable risk factors for a satisfactory outcome. This study aimed to assess the long-term clinical, functional and radiological outcomes in patients after osteosynthesis.

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Article Synopsis
  • Total hip arthroplasty (THA) is an expensive orthopedic procedure affecting healthcare costs significantly in Austria and Switzerland, prompting a comparative cost analysis.
  • Data from national registers and healthcare services revealed similar patient demographics; however, THA costs were lower in both countries when adjusted for inflation but higher in Austria when considering purchasing power.
  • While hospitalization duration decreased substantially in both countries from 2015 to 2021, patients in Austria generally incurred higher costs and stayed longer in the hospital compared to those in Switzerland.
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Article Synopsis
  • * In early 2022, the antibody prevalence was estimated at 74.2% in children across the U.S., while the New Jersey study found a slightly lower prevalence of 68% using the gum swab method.
  • * Results from 86 children showed gum swab sensitivity at 78.7% and specificity at 81.8%, with significant differences noted compared to serology results, indicating limited reliability for the gum swab test.
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Objective: The aim of this study was to compare the outcome of intralesional gross-total resection (GTR) followed by high-energy particle therapy with en bloc and intralesional resections.

Methods: A retrospective study of patients diagnosed with primary osteogenic sarcoma (OGS) of the spine between 2009 and 2020 was conducted. Demographic information, including age, affected site, tumor volume, and Weinstein-Boriani-Biagini stage, was collected.

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  • The study investigates why hip-preserving surgery in young patients often uncovers issues with the ligamentum teres, which may cause hip pain.
  • The research introduces the concept of "fossa-foveolar mismatch" (FFM), comparing the movement of the fovea within the hip joint during daily activities.
  • Results show high reliability in measuring this FFM using a computer-assisted 3D model, demonstrating strong consistency in evaluations between different observers.
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  • The text discusses the risks of avascular necrosis (AVN) in patients with unstable slipped capital femoral epiphysis (SCFE) treated with the modified Dunn procedure, highlighting uncertainties around the classification of instability and its correlation with surgical outcomes.
  • The study aimed to assess the long-term effectiveness of the modified Dunn procedure by measuring the survivorship free from AVN, the need for additional surgeries, and the overall clinical outcomes after 10 years.
  • A total of 159 patients were analyzed, with 58 showing intraoperatively observed epiphyseal-metaphyseal discontinuity, and outcomes were evaluated for a significant majority of these patients, providing important data for future treatment approaches.
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The use of metal-on-metal bearing couples in total hip arthroplasty can lead to an increased release of metal ions, particularly cobalt and chromium over time. This can lead to local and systemic metallosis, which has cytotoxic, genotoxic, and immunotoxic effects and can cause a host of secondary disorders. We describe the case of a 37-year-old female patient that was diagnosed with warm-antibody autoimmune hemolytic anemia (WAIHA) one and a half years after bilateral large-diameter head metal-on-metal total hip arthroplasty.

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Article Synopsis
  • The study examines the role of the ligamentum teres in intraarticular hip pain, particularly its significance in young patients undergoing joint-preserving surgeries, highlighting inconsistencies in previous biomechanical research.
  • Researchers aimed to determine key biomechanical properties of the ligament from patients who had undergone surgical hip dislocation and to analyze any patient-specific factors affecting these properties.
  • The study included 31 participants, all around 27 years old, with the majority being male, and focused on patients with femoroacetabular impingement while excluding those with prior surgeries or specific conditions affecting the hip.
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Introduction: Hip microinstability has become a recognized cause of non-arthritic hip pain and disability in young patients. However, its pathophysiology remains unclear. We want to (1) present an overview of the evidence of hip microinstability and of its association with femoroacetabular impingement (FAI), (2) map out the type of evidence available, and (3) make recommendations for future research.

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Objectives: To compare the prevalence of femoral head decentration (FHD) on different MR imaging planes in patients undergoing direct/indirect hip MR arthrography (MRA) with asymptomatic controls and to evaluate its association with osseous deformities.

Methods: IRB-approved retrospective single-center study of symptomatic hips undergoing direct or indirect hip MRA at 3 T. Asymptomatic participants underwent non-contrast hip MRI at 3 T.

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Study Design: A systemic review and a meta-analysis. We also provided a retrospective cohort for validation in this study.

Objective: (1) Using a meta-analysis to determine the pooled discriminatory ability of The Skeletal Oncology Research Group (SORG) classical algorithm (CA) and machine learning algorithms (MLA); and (2) test the hypothesis that SORG-CA has less variability in performance than SORG-MLA in non-American validation cohorts as SORG-CA does not incorporates regional-specific variables such as body mass index as input.

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Background: Survival estimation for patients with symptomatic skeletal metastases ideally should be made before a type of local treatment has already been determined. Currently available survival prediction tools, however, were generated using data from patients treated either operatively or with local radiation alone, raising concerns about whether they would generalize well to all patients presenting for assessment. The Skeletal Oncology Research Group machine-learning algorithm (SORG-MLA), trained with institution-based data of surgically treated patients, and the Metastases location, Elderly, Tumor primary, Sex, Sickness/comorbidity, and Site of radiotherapy model (METSSS), trained with registry-based data of patients treated with radiotherapy alone, are two of the most recently developed survival prediction models, but they have not been tested on patients whose local treatment strategy is not yet decided.

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Purpose: Autologous matrix-induced chondrogenesis (AMIC) showed promising short-term results comparable to microfracture. This study aims to assess the 19-year outcomes of AMIC, addressing the lack of long-term data.

Methods: Retrospective cohort of 34 knees treated with AMIC underwent a 19-year follow-up.

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Article Synopsis
  • Abnormal femoral head shape from slipped capital femoral epiphysis (SCFE) can lead to hip problems like femoroacetabular impingement and early osteoarthritis, making surgical correction important to restore hip anatomy.
  • The modified Dunn procedure offers a surgical approach that aims to correct the anatomy of the hip without damaging the blood supply to the femoral head, reducing the risk of osteonecrosis.
  • The procedure involves a careful dislocation of the hip and meticulous shaping of bones while maintaining blood vessel integrity, allowing for effective repositioning and fixation of the femoral head.
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A "Think Tank for Osteosarcoma" medical advisory board meeting was held in Santa Monica, CA, USA on February 2-3, 2024. The goal was to develop a strategic approach to prevent recurrence of osteosarcoma. Osteosarcoma metabolism and the genomic instability of osteosarcoma, immunotherapy for osteosarcoma, CAR-T cell therapy, DeltaRex-G tumor-targeted gene therapy, repurposed drugs, alternative medicines, and personalized medicine were discussed.

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Introduction: Despite the benefits of intramedullary nailing (IMN) of impending or pathologic fractures in oncologic patients, literature on patient-reported outcomes (PROs) is scarce in patients treated with carbon fiber (CF) nails. Our study compared postoperative PROs after IMN with CF or titanium implants.

Methods: We conducted a retrospective propensity score-matched cohort study of patients treated at our institution with CF or titanium nails for impending or pathologic fractures from metastatic bone disease.

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Objectives: Metastatic bone disease is estimated to develop in up to 17% of patients with melanoma, compromising skeleton integrity resulting in skeletal-related events (SREs), which impair quality of life and reduce survival. The objective of the study was to investigate (1) the proportion of melanoma patients developing SREs following diagnosis of bone metastasis and (2) the predictors for SREs in this patient cohort.

Methods: Four hundred and eighty-one patients with bone metastatic melanoma from two tertiary centers in the United States from 2008 to 2018 were included.

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