Publications by authors named "Joseph R Pomerening"
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Synopsis of recent research by authors named "Joseph R Pomerening"
- Joseph R Pomerening's research primarily focuses on the regulatory mechanisms of cell cycle progression and metabolic alterations in cancer cells, particularly in relation to cyclin-dependent kinases and anaphase-promoting complexes.
- His findings suggest that manipulation of metabolic pathways, such as through dichloroacetate treatment, can enhance the sensitivity of lung cancer cells to X-ray radiation, indicating potential therapeutic implications for overcoming resistance in tumor cells.
- Pomerening's work also delves into the dynamics of cell cycle oscillations, showcasing how positive feedback loops and bistable mechanisms play pivotal roles in cellular signaling and developmental processes, contributing to our understanding of both normal and aberrant cell cycle behaviors.
