Publications by authors named "Joseph Paradiso"

This study presents a comprehensive dataset capturing indoor environmental parameters, physiological responses, and subjective perceptions across three global cities. Utilizing wearable sensors, including smart eyeglasses, and a modified Cozie app, environmental and physiological data were collected, along with pre-screening, onboarding, and recurring surveys. Peripheral cues facilitated participant engagement with micro-EMA surveys, minimizing disruption over a 5-day collection period.

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Article Synopsis
  • The relationship between thermodynamics and computation has fascinated scientists since the 19th century, but its significance has grown due to the rising energy costs of digital devices.
  • Real-world computers, including biological ones like brains, operate under various physical constraints, which impact their thermodynamic dynamics and efficiency.
  • The emerging field of stochastic thermodynamics offers new analytical techniques to explore how these constraints affect the fundamental thermodynamic properties of systems performing computation.
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We present an approach to develop seamless and scalable piezo-resistive matrix-based intelligent textile using digital flat-bed and circular knitting machines. By combining and customizing functional and common yarns, we can design the aesthetics and architecture and engineer both the electrical and mechanical properties of a sensing textile. By incorporating a melting fiber, we propose a method to shape and personalize three-dimensional piezo-resistive fabric structure that can conform to the human body through thermoforming principles.

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Rapid, accurate and frequent detection of the RNA of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and of serological host antibodies to the virus would facilitate the determination of the immune status of individuals who have Coronavirus disease 2019 (COVID-19), were previously infected by the virus, or were vaccinated against the disease. Here we describe the development and application of a 3D-printed lab-on-a-chip that concurrently detects, via multiplexed electrochemical outputs and within 2 h, SARS-CoV-2 RNA in saliva as well as anti-SARS-CoV-2 immunoglobulins in saliva spiked with blood plasma. The device automatedly extracts, concentrates and amplifies SARS-CoV-2 RNA from unprocessed saliva, and integrates the Cas12a-based enzymatic detection of SARS-CoV-2 RNA via isothermal nucleic acid amplification with a sandwich-based enzyme-linked immunosorbent assay on electrodes functionalized with the Spike S1, nucleocapsid and receptor-binding-domain antigens of SARS-CoV-2.

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Systematically mapping the mechanical properties of skin and tissue is useful for biomechanics research and disease diagnostics. For example, later stage breast cancer and lymphoma manifest themselves as hard nodes under the skin. Currently, mechanical measurements are done manually, with a sense of touch or a handheld tool.

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The standard technology used to capture motion for biomechanical analysis in sports has employed marker-based optical systems. While these systems are excellent at providing positional information, they suffer from a limited ability to accurately provide fundamental quantities such as velocity and acceleration (hence forces and torques) during high-speed motion typical of many sports. Conventional optical systems require considerable setup time, can exhibit sensitivity to extraneous light, and generally sample too slowly to accurately capture extreme bursts of athletic activity.

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The increasing quality and availability of low-cost EEG systems offer new possibilities for non-medical purposes. Existing openly available algorithms to assess the user's mental state in real-time have been mainly performed with medical-grade equipment. In this paper, an approach to assess the user's Focus or Relax states in real-time using a consumer-grade, wearable EEG headband is evaluated.

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We describe a wireless wearable system that was developed to provide quantitative gait analysis outside the confines of the traditional motion laboratory. The sensor suite includes three orthogonal accelerometers, three orthogonal gyroscopes, four force sensors, two bidirectional bend sensors, two dynamic pressure sensors, as well as electric field height sensors. The "GaitShoe" was built to be worn in any shoe, without interfering with gait and was designed to collect data unobtrusively, in any environment, and over long periods.

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