Publications by authors named "Joseph M Cappuccio"

Introduction: Infliximab (IFX) is a standard, inpatient salvage therapy for the treatment of refractory acute severe ulcerative colitis (ASUC). Remicade™ is the originator IFX. Its biosimilar Renflexis™ offers a reduced cost structure.

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Extra pancreatic manifestations of pancreatitis are rare, with a prevalence of 2-3%. One such rare manifestation is the triad of joint pain (polyarthritis), tender skin lesions (panniculitis), and pancreatic inflammation (pancreatitis), known as PPP. The pathogenesis of this phenomenon is not fully understood but is believed to involve lipolysis by pancreatic enzymes at lipid-rich skin and joint sites.

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Introduction: It is unclear if Nosocomial Spontaneous Bacteria Peritonitis (NSBP) is associated with higher mortality compared with community acquired spontaneous bacterial peritonitis.

Methods: Database search from inception to May 2022 was conducted. The databases included MEDLINE, EMBASE, Cochrane registry of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus.

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Background: Hepatic hydrothorax (HH) is associated with a poor prognosis. Liver transplant (LT) is the best treatment modality. We aim to assess post-LT morbidity and mortality in patients with cirrhosis and HH.

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Article Synopsis
  • Waldenström macroglobulinemia (WM) can develop from an asymptomatic stage known as asymptomatic WM (AWM), and this study investigates the risk of progression from AWM to symptomatic WM among 439 patients.
  • The research found that 72% of patients progressed to symptomatic WM over an average of 7.8 years, identifying key predictors of progression such as high immunoglobulin M levels and significant bone marrow infiltration.
  • A new risk classification model was developed and validated, categorizing patients into high, intermediate, and low-risk groups for progression, which can help guide patient monitoring and potential early intervention.
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