Publications by authors named "Joseph Linares"
Article Synopsis
- Tumors develop mutations as they grow, leading to neoantigens that can affect how well patients respond to immune therapies like checkpoint inhibitors.
- The study found a link between the number of clonal neoantigens in lung adenocarcinomas and patient survival, suggesting that the diversity of these neoantigens within tumors plays a crucial role in immune response.
- Patients with advanced lung cancer or melanoma showed better responses to immune therapies when their tumors had a higher presence of clonal neoantigens, highlighting the importance of understanding neoantigen diversity for improving cancer treatments.
