Publications by authors named "Joseph L Chazen"
Background Context: Preoperative imaging for lumbar spine surgery often includes magnetic resonance imaging (MRI) for soft tissues and computer tomography (CT) for bony detail. While CT scans expose patients to ionizing radiation, whereas MRI scans do not. Emerging MRI techniques allow CT-like 3-dimensional (3D) visualization of bony structures, potentially removing the need for ionizing radiation from CT scans.
View Article and Find Full Text PDFSpinal CSF Leaks: The Neuroradiologist Transforming Care.
AJNR Am J Neuroradiol
November 2024
Spinal CSF leak care has evolved during the past several years due to pivotal advances in its diagnosis and treatment. To the reader of the (), it has been impossible to miss the exponential increase in groundbreaking research on spinal CSF leaks and spontaneous intracranial hypotension (SIH). While many clinical specialties have contributed to these successes, the neuroradiologist has been instrumental in driving this transformation due to innovations in noninvasive imaging, novel myelographic techniques, and image-guided therapies.
View Article and Find Full Text PDFArticle Synopsis
- * Accurate diagnosis of these pain types relies on imaging techniques that can distinguish between the two and rule out other conditions, with advancements in MRI enhancing the detection capabilities.
- * The review discusses the mechanisms behind vertebrogenic and discogenic pain and how improved imaging approaches can assist in tailoring personalized treatment plans for affected patients.
Article Synopsis
- The research explores the potential of generating cardiac myocytes from adult rodent bone marrow cells (BMCs) to improve therapies for heart disease.
- The growth factor PDGF-AB was found to significantly increase the speed of myocyte development in vitro and enhance the formation of cardiac myocyte bundles in hearts affected by myocardial infarction.
- However, while PDGF-AB improved generation rates, it did not lead to better heart function compared to treatments using either BMCs or PDGF-AB alone, indicating that maintaining proper cellular arrangement is crucial for restoring heart function effectively.