A computational analysis of the molecular mechanisms underlying the effects of ibuprofen and dibutyl phthalate on gene expression in fish.

The impact of emerging pollutants such as ibuprofen and dibutyl phthalate on aquatic species is a growing concern and the need for proper assessment and evaluation of these toxicants is imperative. The objective of this study was to examine the toxicogenomic impacts of ibuprofen and dibutyl phthalate on , a widely distributed African catfish species. Results showed that exposure to the test compounds caused significant changes in gene expression, including upregulation of growth hormone, interleukin, melatonin receptors, 17β-Hydroxysteroid Dehydrogenase, heat shock protein, doublesex, and mab-3 related transcription factor.

Seasonal Occurrences and Risk Assessment of Phthalate Esters in Sediment, Water and Biota of Two Sub-Saharan Rivers.

The global environmental occurrence of phthalates is inevitable due to their substantial annual production and consumption rate of approximately 5 million tonnes. This study aimed to evaluate the seasonal occurrence of selected phthalate esters congeners in sediment, water, and biota in two freshwater bodies (River Owena and River Ogbese) in Nigeria, and to calculate their ecological risks they pose to aquatic organisms. Dibutyl-phthalate (DBP), di-2-ethylhexyl phthalate (DEHP), and dimethyl-phthalate had an all-year presence in various environmental matrices.

Chronic levels of ibuprofen induces haematoxic and histopathology damage in the gills, liver, and kidney of the African sharptooth catfish (Clarias gariepinus).

Numerous active pharmaceutical ingredients (APIs) have been detected in various environmental matrices. Thus, their potential to elicit their toxic effect on non-target organisms is a growing concern, especially in the aquatic environment. This study aimed to investigate the potential toxicity of ibuprofen (IBU) at environmentally relevant concentration on the haematology and histology of the gill, liver, and kidney over 30 days.

Heavy metals, parasitologic and oxidative stress biomarker investigations in from Lekki Lagoon, Lagos, Nigeria.

Heavy metal toxicity in aquatic life as a result of human activities poses a grave health threat to water quality, aquatic and human life. Parasites may serve as indicators of heavy metal pollution. This research investigated the health status of the fish viz-a-viz quality of the water and sediments in Lekki lagoon, parasitic infection, presence of heavy metals and oxidative stress response in the liver and intestine of the fish.

Bioaccumulation of Polychlorinated Biphenyls (PCBs) in Fish Host-Parasite Bentho-Pelagic Food Chain in Epe Lagoon, Lagos, Nigeria.

This paper investigates the concentrations of PCBs in the water and sediment media and its bio-concentration in the fish host-parasite bentho-pelagic food chain in Epe lagoon. Samples of water, sediment, plankton, mollusks, fish and intestinal helminth parasites were collected from three stations (Oriba, Imode and Ikosi) in Epe Lagoon. Concentration of total PCBs in the surface water and sediment across the stations ranges from 3.

Bioaccumulation of BTEX and PAHs in (Actinopterygii) from the Epe Lagoon, Lagos, Nigeria.

Toxicity studies in the aquatic ecosystem have shown that petrol and its product have adverse effects on aquatic biota. They are able to easily absorb these toxic substances into their bodies from sediment, water or even food items that are contaminated, thus impacting the food chain. In this study, water, sediment and fish () from the Epe Lagoon were investigated for the presence of BTEX (benzene, toluene, ethylbenzene and the three xylene isomers m, o and p-xylenes), and PAHs using GC-MS.

Biomonitoring, physico-chemical, and biomarker evaluations of abattoir effluent discharges into the Ogun River from Kara Market, Ogun State, Nigeria, using Clarias gariepinus.

The discharge of untreated effluents into aquatic ecosystems poses potential adverse effects to aquatic organisms. In this study, the physico-chemical characteristics of abattoir effluent from Kara Cow Market, Ogun State, Nigeria, surface water and sediments from the Ogun River were evaluated. Fish species and macrobenthic fauna diversity in the river were also examined.

Biochemical Effects of the Toxic Interaction of Copper, Lead and Cadmium on Clarias gariepinus.

Background: The presence of heavy metals in the aquatic environment is a concern because of potential toxicity and threats to plant and animal life.

Objective: The present study evaluated the joint action toxicity and biochemical effects of sublethal concentrations of copper (Cu), lead (Pb) and cadmium (Cd) against Clarias gariepinus over a period of 28 days.

Methods: We procured fingerlings (weight: 5-8 g; length: 4.