Evaluation of Viscoelastic Properties, Blood Coagulation, and Cellular Responses of a Temperature-Sensitive Gel for Hemostatic Application.

Hemorrhagic blood loss from traumatic injury is the leading cause of death in severe accidents and combat injuries. Treating and stopping blood loss in a timely and effective manner is essential for the survival of the patient. Currently, QuikClot and dry fibrin sealant dressing are well-known approaches for hemostatic treatment.

Heterogenous population coding of a short-term memory and decision task.

We examined neural spike recordings from prefrontal cortex (PFC) while monkeys performed a delayed somatosensory discrimination task. In general, PFC neurons displayed great heterogeneity in response to the task. That is, although individual cells spiked reliably in response to task variables from trial-to-trial, each cell had idiosyncratic combinations of response properties.

Development of neural circuitry for precise temporal sequences through spontaneous activity, axon remodeling, and synaptic plasticity.

Temporally precise sequences of neuronal spikes that span hundreds of milliseconds are observed in many brain areas, including songbird premotor nucleus, cat visual cortex, and primary motor cortex. Synfire chains-networks in which groups of neurons are connected via excitatory synapses into a unidirectional chain-are thought to underlie the generation of such sequences. It is unknown, however, how synfire chains can form in local neural circuits, especially for long chains.

Formation and structure of ramified charge transportation networks in an electromechanical system.

We present findings in an experiment where we obtain stationary ramified transportation networks in a macroscopic nonbiological system. Our purpose here is to introduce the phenomenology of the experiment. We describe the dynamical formation of the network which consists of three growth stages: (I) strand formation, (II) boundary formation, and (III) geometric expansion.