Publications by authors named "Joseph J L Vadakara"
Importance: Acute promyelocytic leukemia (APL) is an acute illness that presents with cytopenia, infections, and disseminated intravascular coagulation. Achieving remission has been shown to make a major difference in patient outcomes; however, early death rates in the first month have been as high as 30% due to acute presentation, comorbidities, the rarity of APL, and clinician inexperience.
Objective: To develop treatment strategies that would decrease estimated 1-month mortality from 30% to below 15%.