Transitions of frailty after lower extremity interventions for chronic limb-threatening ischemia.

Background: Frailty is common among surgical patients and predicts poor surgical outcomes. This study aimed to analyze transitions in frailty state among patients undergoing lower extremity care for chronic limb-threatening ischemia (CLTI).

Methods: Between 2018 and 2022, all patients undergoing a primary intervention for CLTI (endovascular intervention [EV], bypass [BYP], major amputation [AMP]) or wound care were analyzed.

The Value of Restaging WIfI (Wound, Ischemia, and Foot Infection) After Initial Vascular and Podiatric Intervention.

Background: Wound, ischemia, and foot infection (WIfI) is an important staging system for diabetic patients presenting with chronic limb-threatening ischemia (CLTI) of the lower extremities (LEs). This study examines the clinical implications of restaging WIfI after initial vascular and podiatric interventions.

Methods: A prospective database of patients undergoing vascular intervention treatment of the LE for tissue loss between 2018 and 2022 was queried.

Comparing cancer stage at diagnosis between migrants and non-migrants: a meta-analysis.

Background: Migrants face barriers accessing healthcare, risking delays in cancer diagnosis. Diagnostic delays result in later stage diagnosis which is associated with poorer cancer survival. This review aims to compare the differences in cancer stage at diagnosis between migrants and non-migrants.

Neuromuscular Performance and the Intensity of External Training Load During the Preseason in National Collegiate Athletic Association Division I Men's Collegiate Basketball Players.

Curtis, M, Kupperman, N, Westbrook, J, Weltman, AL, Hart, J, and Hertel, J. Neuromuscular performance and the intensity of external training load during the preseason in National Collegiate Athletic Association Division I men's collegiate basketball players. J Strength Cond Res 39(1): 54-61, 2025-The aim of the study was to determine whether acute changes in neuromuscular performance can be detected through countermovement jumps (CMJs) conducted pre- and postpractice sessions in conditions of high or low intensity measured by microsensors technology.

The efficiency of synchronization dynamics and the role of network syncreactivity.

Synchronization of coupled oscillators is a fundamental process in both natural and artificial networks. While much work has investigated the asymptotic stability of the synchronous solution, the fundamental question of the transient behavior toward synchronization has received far less attention. In this work, we present the transverse reactivity as a metric to quantify the instantaneous rate of growth or decay of desynchronizing perturbations.

Vascular Complications in Extracorporeal Membrane Oxygenation-A Narrative Review.

The establishment of a peripheral ECMO circuit can lead to significant arterial and venous complications in 10-30% of patients. Vascular complications, particularly acute limb ischemia, are associated with worsening overall outcomes. Limb ischemia occurs significantly more frequently in the early stages of VA ECMO than in VV ECMO.

Photonic next-generation reservoir computer based on distributed feedback in optical fiber.

Reservoir computing (RC) is a machine learning paradigm that excels at dynamical systems analysis. Photonic RCs, which perform implicit computation through optical interactions, have attracted increasing attention due to their potential for low latency predictions. However, most existing photonic RCs rely on a nonlinear physical cavity to implement system memory, limiting control over the memory structure and requiring long warm-up times to eliminate transients.

The effect of factors from different time points on psychological readiness following ACL reconstruction.

Objective: The purpose of this study was to examine factors correlated with psychological readiness to return to activity after ACLR.

Design: cross sectional study.

Setting: controlled laboratory.

Pedal medial arterial calcification influences the outcomes of isolated infra-malleolar interventions for chronic limb-threatening ischemia.

Objective: Inframalleolar disease is present in most diabetic patients presenting with tissue loss. Inframalleolar (pedal) artery disease and pedal medial arterial calcification (pMAC) are associated with major amputation in patients with chronic limb-threatening ischemia (CLTI). This study aimed to examine the impact of pMAC on the outcomes after isolated inframalleolar (pedal artery) interventions.

Transference of outdoor gait-training to treadmill running biomechanics and strength measures: A randomized controlled trial.

Outdoor gait-training has been successful in improving pain and reducing contact time during outdoor running for runners with exercise-related lower leg pain (ERLLP). However, it is unclear if these adaptations translate to gold standard treadmill running and clinical strength assessments. The study purpose was to assess the influence of a 4-week outdoor gait-training intervention with home exercises (FBHE) on treadmill running biomechanics and lower extremity strength compared to home exercises alone (HE) among runners with ERLLP.

Management of depth to achieve timely arteriovenous fistula utilization.

Objective: Failure to achieve timely arteriovenous fistulae (AVFs) utilization due to excessive depth (>6 mm) remains an ongoing concern for dialysis access. This study evaluates the outcomes of radiocephalic (RCF) and brachiocephalic (BCF) fistula elevation required for access utilization.

Methods: A retrospective review of all patients undergoing first-time autologous access over 10 years was undertaken.

Extracorporal Membrane Oxygenation in Massive Pulmonary Embolism.

Background: Massive pulmonary embolism (MPE) carries significant 30-day mortality risk, and a change in societal guidelines has promoted the increasing use of extracorporeal membrane oxygenation (ECMO) in the immediate management of MPE-associated cardiovascular shock. This narrative review examines the current status of ECMO in MPE.

Methods: A literature review was performed from 1982 to 2022 searching for the terms "Pulmonary embolism" and "ECMO," and the search was refined by examining those publications that covered MPE.

Attractor reconstruction with reservoir computers: The effect of the reservoir's conditional Lyapunov exponents on faithful attractor reconstruction.

Reservoir computing is a machine learning framework that has been shown to be able to replicate the chaotic attractor, including the fractal dimension and the entire Lyapunov spectrum, of the dynamical system on which it is trained. We quantitatively relate the generalized synchronization dynamics of a driven reservoir during the training stage to the performance of the trained reservoir computer at the attractor reconstruction task. We show that, in order to obtain successful attractor reconstruction and Lyapunov spectrum estimation, the maximal conditional Lyapunov exponent of the driven reservoir must be significantly more negative than the most negative Lyapunov exponent of the target system.

Evaluation of Differences in Patellar Height After Patellar Stabilization Procedures Not Intended to Address Patella Alta: A Multicenter Study.

Background: Recent studies have reported conflicting results as to whether isolated medial patellofemoral ligament reconstruction (MPFLr) leads to decreased patellar height.

Purpose: To investigate if patellar stabilization surgery not intended to address patella alta influences patellar height.

Study Design: Cohort study; Level of evidence, 3.

Endovascular management of acute and subacute venous thoracic outlet syndrome.

Approximately 3% of all patients presenting with Thoracic Outlet Syndrome have a venous etiology (vTOS), which is considered "effort thrombosis". These patients will present with symptomatic deep venous thrombosis or focal subclavian vein (SCV) stenosis. Endovascular management of vTOS occurs in several phases: diagnostic, preoperative therapeutic intervention before decompression, postoperative interventions after decompression, and delayed interventions in the follow-up after decompression.

Current status of ECMO for massive pulmonary embolism.

Massive pulmonary embolism (MPE) carries significant 30-day mortality and is characterized by acute right ventricular failure, hypotension, and hypoxia, leading to cardiovascular collapse and cardiac arrest. Given the continued high mortality associated with MPE, there has been ongoing interest in utilizing extracorporeal membrane oxygenation (ECMO) to provide oxygenation support to improve hypoxia and offload the right ventricular (RV) pressure in the belief that rapid reduction of hypoxia and RV pressure will improve outcomes. Two modalities can be employed: Veno-arterial-ECMO is a reliable process to decrease RV overload and improve RV function, thus allowing for hemodynamic stability and restoration of tissue oxygenation.

Estimating the master stability function from the time series of one oscillator via reservoir computing.

The master stability function (MSF) yields the stability of the globally synchronized state of a network of identical oscillators in terms of the eigenvalues of the adjacency matrix. In order to compute the MSF, one must have an accurate model of an uncoupled oscillator, but often such a model does not exist. We present a reservoir computing technique for estimating the MSF given only the time series of a single, uncoupled oscillator.

Synchronizing chaos using reservoir computing.

We attempt to achieve complete synchronization between a drive system unidirectionally coupled with a response system, under the assumption that limited knowledge on the states of the drive is available at the response. Machine-learning techniques have been previously implemented to estimate the states of a dynamical system from limited measurements. We consider situations in which knowledge of the non-measurable states of the drive system is needed in order for the response system to synchronize with the drive.

No Deficits in Functional Outcomes of the Contralateral Limb Are Seen When the Hamstring Is Harvested for Augmentation of Small Diameter Ipsilateral Hamstring Autograft.

Purpose: To evaluate clinical outcomes of the contralateral, nonoperative limb in patients undergoing contralateral hamstring (HS) autograft harvest compared with patients undergoing ipsilateral HS autograft harvest alone.

Methods: This study included 96 patients who underwent isolated anterior cruciate ligament reconstruction (ACLR) using 4-stranded HS autograft (n = 85) or 4-stranded HS autograft augmented with contralateral HS (n = 13) due to inclusion of ipsilateral graft diameter <8 mm. Isokinetic flexion and extension strength and dynamic performance of the ipsilateral and contralateral limbs and limb symmetry index (LSI) were evaluated at 6 months' postoperatively.

Development and Evaluation of an Enhanced Recovery Protocol to Reduce Length of Stay following Elective Endovascular Aneurysm Repair.

Background: Elective endovascular abdominal aortic aneurysm repair (EVAR) can be performed safely with a short postoperative length of stay (LOS). We aimed to develop and assess the impact of an enhanced recovery protocol (ERP) on LOS after elective EVAR.

Methods: Pre-ERP development single center retrospective review of elective EVAR procedures from January 2012 to December 2019.

Athlete Muscular Phenotypes Identified and Compared with High-Dimensional Clustering of Lower Limb Muscle Volume Measurements.

Introduction: Athletes use their skeletal muscles to demonstrate performance. Muscle force generating capacity is correlated with volume, meaning that variations in sizes of different muscles may be indicative of how athletes meet different demands in their sports. Medical imaging enables in vivo quantification of muscle volumes; however, muscle volume distribution has not been compared across athletes of different sports.

Time-shift selection for reservoir computing using a rank-revealing QR algorithm.

Reservoir computing, a recurrent neural network paradigm in which only the output layer is trained, has demonstrated remarkable performance on tasks such as prediction and control of nonlinear systems. Recently, it was demonstrated that adding time-shifts to the signals generated by a reservoir can provide large improvements in performance accuracy. In this work, we present a technique to choose the time-shifts by maximizing the rank of the reservoir matrix using a rank-revealing QR algorithm.