Publications by authors named "Joseph H Jeffrey"

We describe a case of orbital cellulitis with abscess formation following eyebrow piercing complicated by internal jugular vein thrombosis and subretinal abscesses requiring enucleation with orbital abscess drainage. The popularity of body piercing is increasing and physicians should be familiar with the possibility and management of vision-threatening complications of facial piercing. Following left eyebrow piercing, a 20-year-old female experienced increasing periorbital swelling, erythema, chemosis, orbital pain, decreased vision, and concomitant fever, chills, and rhinorrhea.

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Purpose: The aim of this study was to report outcomes after allogeneic ocular surface stem cell transplantation (OSST) for limbal stem cell deficiency in the setting of decreased or no systemic immunosuppression (SI) in the elderly.

Methods: A retrospective chart review was performed of all eyes that underwent OSST for limbal stem cell deficiency between 2005 and 2020 at CVP Physicians. Inclusion criteria included patients who were (1) at least 70 years at the time of (2) allogeneic OSST.

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Article Synopsis
  • The study aimed to examine how the number of penetrating keratoplasty (PK) procedures affects postoperative panel reactive antibody (PRA) levels and the number of unacceptable antigens in patients.
  • A cross-sectional study was conducted, excluding patients with solid organ transplants, pregnancy, or blood transfusions, and focused on comparing patients with single vs. multiple PKs.
  • Results showed that those with multiple PKs had higher PRA levels and a greater number of unacceptable antigens, indicating a correlation between the number of PKs and PRA levels that warrants further investigation.
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Purpose: Panel-reactive antibody (PRA) testing has been widely adopted in solid organ transplantation for risk assessment in potential allograft recipients but has not been studied in the context of ophthalmic transplantation. The purpose of this study is to evaluate outcomes in patients undergoing ocular surface stem cell transplantation (OSST) for limbal stem cell deficiency (LSCD) relative to preoperative PRA level.

Methods: This is retrospective chart review of all eyes with documented PRA level that underwent OSST for LSCD between May 2000 and March 2019 at a single institution.

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