Publications by authors named "Joseph G Ouzounian"
Article Synopsis
- - The study evaluated trends and outcomes of gestational carrier (GC) pregnancies in the U.S. using data from over 14 million deliveries between 2017 and 2020, finding that the prevalence of GC pregnancies rose by 55% during this period.
- - Among GCs, there was a higher likelihood of complications such as multiple pregnancies, placental abruption, and low-lying placenta, along with increased risks for late-preterm deliveries and postpartum hemorrhage in singleton births compared to non-GCs.
- - While GC pregnancies are relatively rare, the findings indicate they are becoming more common and generally have favorable pre-pregnancy characteristics, but their obstetric outcomes can be mixed, especially regarding certain complications. *
In this nationwide cross‐sectional study in the United States, clinical and gynecologic characteristics varied across the anatomical site of ectopic pregnancy.
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- Advancements in assisted reproductive technology have led to a rise in gestational carrier pregnancies, highlighting the need for more research on their perinatal outcomes and associated risks.
- The objective of the study was to analyze maternal characteristics and obstetric outcomes in pregnancies involving gestational carriers.
- A systematic review included six studies analyzing over 28,000 GC pregnancies, revealing higher rates of frozen embryo transfers and comparing various obstetric outcomes with non-GC pregnancies.
Article Synopsis
- A study was conducted to analyze obstetric outcomes in pregnant women with congenital uterine anomalies using data from the Nationwide Inpatient Sample between 2016 and 2019.* -
- Out of 50,180 women assessed, the majority had a bicornuate uterus, with 70.6% achieving full-term live births, while 26.8% experienced preterm births.* -
- The findings highlighted that women with uterine didelphys had the highest rates of preterm births, and 65.7% of all patients underwent cesarean sections, with increased risks of severe maternal morbidity associated with septate uteri.*
Objective: To examine pregnancy characteristics and maternal morbidity at delivery among pregnant patients with a diagnosis of endometriosis.
Study Design: This cross-sectional study queried the Healthcare Cost and Utilization Project's National Inpatient Sample. Study population was 17,796,365 hospital deliveries from 2016 to 2020, excluded adenomyosis and uterine myoma.
Article Synopsis
- The study aimed to evaluate clinical and pregnancy characteristics, surgical practices, and complications from cesarean hysterectomy performed due to placenta accreta spectrum, focusing on the surgeon's specialty.
- Data were analyzed from the Premier Healthcare Database for patients who had cesarean deliveries and hysterectomies between 2016 and 2020, comparing outcomes based on different types of surgeons: general obstetricians, maternal-fetal medicine specialists, and gynecologic oncologists.
- Results showed that while the types of surgeons varied, surgical complications such as hemorrhage and bladder injuries were comparable across the groups, but gynecologic oncologists had patients with more severe cases (placenta increta/percreta) and specific surgical
Article Synopsis
- The study aimed to evaluate trends and outcomes of pregnancies in women with Turner syndrome in the U.S. using data from hospital deliveries between 2016 and 2020.
- Turner syndrome prevalence among pregnant patients was found to be 7.0 per 100,000 deliveries, with an increase in cases during the study period, suggesting a rising recognition of the condition.
- Pregnant women with Turner syndrome faced higher risks of various complications, such as pregestational hypertension, intrauterine fetal demise, and were more likely to have cesarean deliveries compared to those without the syndrome.
Article Synopsis
- The study investigates the maternal and fetal health outcomes in morbidly obese pregnant women who conceived using assisted reproductive technology (ART), focusing on data from a significant national sample.
- It finds that patients with class III obesity (severe obesity) are at a notably higher risk for complications like hypertensive disorders, diabetes, and adverse neonatal outcomes compared to non-obese patients.
- Overall, the research indicates that severe obesity in pregnancy is linked to an increased likelihood of severe maternal morbidity, highlighting the need for tailored healthcare interventions for this population.
Article Synopsis
- Gallstone disease is a common reason for nonobstetrical surgery during pregnancy, but there's limited national data on current surgical practices and outcomes.* -
- The study analyzed data from 18,630 patients who underwent cholecystectomy during pregnancy between 2016 and 2020, focusing on different gestational age groups and their associated medical characteristics and outcomes.* -
- Findings revealed that early second trimester had the highest surgery rate, with distinct health issues identified in different trimesters, such as older age and smoking in the first trimester, and obesity and gestational diabetes in the third trimester.*
Background: The risk of third- and fourth-degree perineal laceration after vaginal delivery in patients with obesity is relatively understudied and has mixed findings in existing literature.
Objective: This study aimed to examine the association of maternal obesity and obstetric anal sphincter injuries at vaginal delivery.
Study Design: The Healthcare Cost and Utilization Project's National Inpatient Sample was retrospectively queried to examine 7,385,341 vaginal deliveries from January 2017 to December 2019.
Introduction: Since malignancy during pregnancy is uncommon, information regarding contraception selection or sterilization at delivery is limited. The objective of this study was to examine the type of long-acting reversible contraception or surgical sterilization procedure chosen by pregnant patients with malignancy at delivery.
Material And Methods: This cross-sectional study queried the Healthcare Cost and Utilization Project's National Inpatient Sample in the USA.
Article Synopsis
- Previous cesarean deliveries increase the risk of developing placenta accreta spectrum in later pregnancies, prompting concerns for patients attempting vaginal birth after cesarean delivery (VBAC).
- This study analyzed data from over 184,000 patients who had undergone vaginal deliveries following previous low transverse cesarean deliveries to assess the incidence, characteristics, and outcomes of unsuspected placenta accreta spectrum.
- The results revealed an incidence rate of 8 for placenta accreta spectrum among those delivering vaginally after a cesarean, along with a focus on maternal morbidity and clinical outcomes.
Placenta accreta spectrum encompasses cases where the placenta is morbidly adherent to the myometrium. Placenta percreta, the most severe form of placenta accreta spectrum (grade 3E), occurs when the placenta invades through the myometrium and possibly into surrounding structures next to the uterine corpus. Maternal morbidity of placenta percreta is high, including severe maternal morbidity in 82.
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- Unhoused status is a significant issue in the U.S., particularly affecting maternal health during pregnancy, which is being researched to improve health outcomes for those experiencing homelessness.
- The study utilized data from the Healthcare Cost and Utilization Project National Inpatient Sample, focusing on hospital deliveries between 2016 and 2020 to analyze trends and characteristics related to pregnant patients without stable housing.
- The findings revealed a notable increase in the prevalence of unhoused patients during this period, with an increase of 72.1%, highlighting the need for targeted health interventions for this vulnerable group.
Background: Although intrauterine devices provide effective contraceptive protection, unintentional pregnancy can occur. Previous studies have shown that a retained intrauterine device during pregnancy is associated with adverse pregnancy outcomes but there is a paucity of nationwide data and analysis.
Objective: This study aimed to describe characteristics and outcomes of pregnancies with a retained intrauterine device.
Background: Gravid uterine prolapse refers to abnormal descent of the uterus during pregnancy. It is a rare pregnancy complication and its clinical characteristics and obstetrical outcomes are not well understood.
Objective: This study aimed to assess the national-level incidence, characteristics, and maternal outcomes of pregnancies complicated by gravid uterine prolapse.
Article Synopsis
- A study investigated the link between assisted reproductive technology (ART) and various abnormal placentation issues in pregnancies, using data from nearly 15 million deliveries between 2012 and 2015.
- The findings revealed that pregnancies resulting from ART had significantly higher risks for conditions like placenta accreta spectrum (PAS), placenta previa (PP), and vasa previa (VP) compared to those conceived without ART.
- Additionally, pregnancies after ART were more likely to experience multiple abnormal placentation issues simultaneously, highlighting the potential complications associated with ART.
Article Synopsis
- This study investigated how uterine adenomyosis affects obstetric outcomes in women aged 15-54 during hospital deliveries from 2016 to 2019.
- Using a large dataset, researchers found that women with adenomyosis had higher odds of serious placental complications like placenta previa, accreta, and abruption, and were more likely to have premature deliveries and cesarean sections.
- Overall, the findings indicate that uterine adenomyosis is linked to an increased risk of severe complications for both mothers and infants during childbirth.