Publications by authors named "Joseph Bouchard"
Background: Stress cardiomyopathy (SCM) is a syndrome of transient ventricular dysfunction triggered by severe emotional or physical stress, likely resulting from catecholamine-mediated myocardial toxicity. Repolarization abnormalities associated with other hyperadrenergic states can cause QT prolongation and lethal arrhythmia including torsades de pointes (TdP). Despite the development of repolarization abnormalities and QT prolongation in SCM, little is known about the risk of ventricular fibrillation (VF) and TdP.
View Article and Find Full Text PDFTransient stress cardiomyopathy (TSC) is a cause of reversible left ventricular (LV) dysfunction that is increasingly recognized. Reports to date have focused primarily on LV involvement, with little attention paid to associated right ventricular (RV) dysfunction. With other forms of LV dysfunction, RV involvement has been shown to confer an adverse prognosis.
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- * It found that Doppler echocardiographic methods can reliably estimate PAWP in many patients, especially when excluding those with liver or pulmonary issues.
- * The results show strong correlations between PASP and measured PAWP, aiding in distinguishing between low and high PAWP, which is important for patient diagnosis and treatment.
Article Synopsis
- A study analyzed clinical and echocardiographic data from 533 patients hospitalized with acute heart failure, focusing on those aged 85 and older, to fill a gap in existing research.
- The data indicated that the oldest patients (average age 91.9) had the highest percentage of heart failure cases with preserved left ventricular ejection fraction at 61%, compared to younger age groups (48% for both 65-74 and 75-84 years).
- The majority of the oldest patients were women, with around two-thirds exhibiting a left ventricular ejection fraction of 50% or higher.
The goal of these experiments was to understand DNA changes relevant to schizophrenia. This work compared DNA of monozygotic (MZ) twins surrounding (CAG)(n) repeating sequences, and characterized the relationship between fragile sites and schizophrenia. Twelve twin-pairs, previously classified as MZ and 18 unrelated sib-pairs, from seven families were studied.
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