Publications by authors named "Joseph Both"
Article Synopsis
- Hypofractionated radiotherapy for prostate cancer requires the right treatment margins to balance tumor control and minimize side effects, which have not been standardized before.
- In a study with 16 patients, a specific dose was delivered in 5 fractions, and daily imaging was used to track treatment and adjust doses accurately.
- The results showed that while the overall coverage for the planned treatment area decreased, prostate coverage was maintained, indicating that current margins are effective, although a boost is needed for higher-risk areas.
Article Synopsis
- Adaptive radiotherapy (ART) is being assessed for its effectiveness in patients with head and neck cancer, particularly those with bulky disease, as it can accommodate changes in tumor volume and weight loss during treatment.
- A study involving 20 patients revealed a higher occurrence of ART-triggering events in those with bulky disease compared to postoperative patients, indicating a greater need for adjustments in treatment for the former group.
- The findings suggest that patients with bulky disease often experience issues like spinal cord overdose and inadequate coverage of clinical target volumes, emphasizing the importance of monitoring and potentially utilizing ART for better treatment outcomes.
This work is a report on the commissioning of low energy electron beams of a medical linear accelerator for Monte Carlo dose calculation using NXEGS software (NXEGS version 1.0.10.
View Article and Find Full Text PDFIt is demonstrated that the minimization of the free energy functional for hard spheres and hard disks yields the result that excited granular materials under gravity segregate not only in the widely known "Brazil nut" fashion, i.e., with the larger particles rising to the top, but also in reverse "Brazil nut" fashion.
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