Publications by authors named "Joseph A Stapleton"

Single-walled carbon nanotubes (SWNT) are attractive targets for the formation of high-density sensor arrays. Their small size and high reactivity could allow for the spatial and temporal study of extracellular products to a degree which greatly surpasses contemporary sensors. However, current methods of SWNT immobilization produce a low fluorescence yield that requires a combination of high magnification, exposure time, and laser intensity to combat, thus limiting the sensor's applications.

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The use of nanoparticles within living systems is a growing field, but the long-term effects of introducing nanoparticles to a biological system are unknown. If nanoparticles remain localized after in vivo implantation unanticipated side effects due to unknown biodistribution can be avoided. Unfortunately, stabilization and retention of nanoparticles frequently alters their function.

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