Publications by authors named "Joselo Ramon Martinez-Rosas"
Modification of Proliferation and Apoptosis in Breast Cancer Cells by Exposure of Antioxidant Nanoparticles Due to Modulation of the Cellular Redox State Induced by Doxorubicin Exposure.
Laura Denise López-Barrera Roberto Díaz-Torres Joselo Ramón Martínez-Rosas Ana María Salazar Carlos Rosales
Pharmaceutics
August 2021
Article Synopsis
- The report examines how chitosan-carrying-glutathione nanoparticles (CH-GSH NPs) can influence breast cancer cell behaviors like proliferation and apoptosis, while also mitigating doxorubicin's toxicity.
- CH-GSH NPs were found to enhance levels of glutathione, a natural antioxidant, and lower harmful reactive oxygen species when combined with doxorubicin treatment.
- The study suggests that CH-GSH NPs could serve as a promising delivery system for reducing the side effects of cancer therapies, potentially benefiting fields like pharmacy and biomedicine.