Publications by authors named "Josefina Lascano-Maillard"
Simultaneous isolation of endothelial and alveolar epithelial type I and type II cells during mouse lung development in the absence of a transgenic reporter.
Yves Donati Sanja Blaskovic Isabelle Ruchonnet-Métrailler Josefina Lascano Maillard Constance Barazzone-Argiroffo
Am J Physiol Lung Cell Mol Physiol
April 2020
Article Synopsis
- Mouse lung development starts at birth, focusing on alveolar cells that change shape to form the alveoli lining.
- Researchers created a method to isolate alveolar epithelial and endothelial cells during key developmental phases, identifying immature AEC type I expressing high podoplanin levels on postnatal day 2.
- Maturation of these cells led to lower isolation yields and a change in marker expression, specifically an increase in MHCII in AEC type II by postnatal day 8, suggesting their role in lung alveolarization.
Evidence of the mediation of glycan molecules in the interaction between viruses and their hosts is accumulating and is now partially reflected in several online databases. Bioinformatics provides convenient and efficient means of searching, visualizing, comparing, and sometimes predicting, interactions in numerous and diverse molecular biology applications related to the -omics fields. As viromics is gaining momentum, bioinformatics support is increasingly needed.
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