Publications by authors named "Josefiina Haalisto"
Article Synopsis
- Long non-coding RNAs (lncRNAs) are significant in the progression of cutaneous squamous cell carcinoma (cSCC), a common and aggressive skin cancer with poor prognosis and no current biomarkers for metastasis risk.
- RNA sequencing analysis revealed six gene clusters, showing that upregulated lncRNAs are linked to increased cell motility in cSCC and head and neck SCC (HNSCC).
- Specifically, higher levels of lncRNAs HOTTIP and LINC00543 were found in tumor samples and correlated with worse outcomes, suggesting these lncRNAs could serve as new biomarkers or potential targets for therapies in metastatic cSCC.
