Publications by authors named "Jose-Antonio Mondragon"
Article Synopsis
- * The study found that CRS boosts TPH2 expression and activity specifically in the left adrenal gland while decreasing TPH levels in the dorsal raphe nucleus (DRN), which is involved in serotonin production.
- * Overall, the results suggest that CRS leads to higher serotonin synthesis in the adrenal glands due to increased TPH2, highlighting a complex interaction between stress and hormone regulation in the body.
Glioblastoma (GB) is the most common and aggressive primary brain tumour in adult humans. Therapeutic resistance and tumour recurrence after surgical removal contribute to poor prognosis for glioblastoma patients. Men are known to be more likely than women to develop an aggressive form of GB, and differences in sex steroids have emerged as a leading explanation for this finding.
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