Publications by authors named "Jose Vicente Serna Berna"
An Pediatr (Engl Ed)
August 2022
Article Synopsis
- Hypogammaglobulinemia is common in pediatric patients following allogeneic hematopoietic stem cell transplantation (HSCT), often requiring immunoglobulin replacement therapy to prevent infections, especially when it persists over time.
- A study from 2008-2019 evaluated pediatric patients with persistent chronic hypogammaglobulinemia, analyzing the transition from intravenous immunoglobulin (Privigen®) to subcutaneous immunoglobulin (Hizentra®) and its effects on patients’ quality of life.
- The findings indicate that chronic hypogammaglobulinemia results from various factors, and while the study had a small sample size, switching to Hizentra 20% significantly improved the patients
