Characteristics and prevalence of orofacial pain as an initial symptom of oral and oropharyngeal cancer and its impact on the patient's functionality and quality of life.

Objective: To evaluate the prevalence and characteristics of orofacial pain in oral and oropharyngeal cancer (OOC), at diagnosis.

Material And Methods: a) Study group (SG; n = 74) patients with cancer were divided into 2 subgroups: oral cancer (OC) and oropharyngeal cancer (OPC); b) control group (CG; n = 74) patients within dental care.

Study Design: An Orofacial Pain Assessment, verbal descriptive scale, Helkimo dysfunction index, Quality of Life questionnaire, and Karnofsky performance status (KPS) was used for evaluation.

Sensory characteristics and chronic facial pain conditions: Cross-sectional study.

Objectives: This study investigated patients with neuropathic, myofascial and other orofacial pain conditions according to the differences and similarities of the sensory profile, and the association between sensory findings and neuropathic or non-neuropathic conditions.

Design: 132 healthy controls were compared with 174 orofacial pain patients that were classified into three groups (neuropathic, masticatory myofascial and other orofacial pain condition) and evaluated with a systematized protocol of sensory testing. Data were analyzed with chi-quare and Bonferroni correction (categorical data), Student´s t test, oneway ANOVA, Tukey (quantitative features), Pearson´s coefficient for correlations and logistic regression.

Sensory characteristics according to chronic diseases and chronic pain in adults: cross-sectional study.

 To investigate somatosensory, gustative and olfactory characteristics of subjects according to their chronic diseases and the presence of chronic pain complaints.  A total of 254 chronic pain patients and 52 healthy subjects were evaluated with a clinical and sensory systematized evaluation. Statistical analysis consisted of Fisher's exact, Student's t-tests, Pearson's co-efficient and multivariate nonlinear/logistic regressions.

Increased Anxiety-Like Behavior in the Acute Phase of a Preclinical Model of Periodontal Disease.

Periodontal disease (PD) is an infectious-inflammatory oral disease that is highly prevalent among adolescence and adulthood and can lead to chronic orofacial pain and be associated with anxiety, stress and depression. This study aimed to identify anxiety-like behaviors in the ligature-induced murine preclinical model of PD in different phases of the disease (i.e.

Association between craniofacial pain complaints, somatoform symptoms and chronic diseases.

Objective: This case-control study aimed to investigate associations between craniofacial pain complaints, somatoform symptoms and chronic diseases.

Design: 306 subjects were included in this study (174 patients and 132 healthy subjects). The evaluation consisted of demographic data, number of functional and nonfunctional chronic diseases, medications, somatoform symptoms (xerostomia, dry mucosa, numbness, gastrointestinal complaints), and pain complaints with associated characteristics (number of pain areas, sensation of tired face, bruxism, sleep disturbances, masticatory musculoskeletal evaluation).

Balloon compression vs radiofrequency for primary trigeminal neuralgia: a randomized, controlled trial.

Surgical procedures are necessary in up to 50% of trigeminal neuralgia patients. Although radiofrequency (RF) is more widely used, it is associated with high intraprocedural costs and long technical learning time. Other simpler procedures such as balloon compression (BC) require a lower training period and have significant lower costs.

The Orofacial Pain Clinic Questionnaire (EDOF-HC) in the evaluation and diagnosis of orofacial pain.

Background: Diagnostic tools are necessary for the anamnesis and examination of orofacial pain, in order to fulfill diagnostic criteria and to screen potential causes of pain.

Objective: To evaluate the Orofacial Pain Clinic Questionnaire (EDOF-HC) in the assessment and diagnosis of orofacial pain.

Methods: Overall, 142 patients were evaluated and classified according to the criteria of the International Headache Society and International Association for the Study of Pain.

Chronic facial pain: different comorbidities and characteristics between neuropathic and nonneuropathic conditions.

Objective: The aim of this study was to investigate the association between comorbidities and chronic diseases and neuropathic and nonneuropathic orofacial pain diagnoses to suggest subclassifications of disease.

Study Design: This was a cross-sectional, retrospective, case-control study. We evaluated 174 patients with orofacial pain and 132 controls by using a systematic protocol that consisted of medical history and demographic, pain, and orofacial characteristics.

Chronic pain, somatic unexplained complaints and multimorbidity: A mutimorbidity painful syndrome?

Introduction: Chronic illnesses are a major research challenge due to its implications in aging and quality of life of adults and elders, and it can be associated with chronic illnesses and other complaints. The objective of this study was to investigate the role of morbidities (chronic diseases with or without somatic unexplained symptoms) and somatic unexplained complaints in a hypothetical model of a multimorbidity painful syndrome. Our hypothesis is that chronic pain should be considered part of a syndrome that includes other chronic diseases and pathological states, especially conditions with somatic unexplained symptoms, and fibromyalgia is one of the evidence on that.

Quantitative sensory testing in elderly: longitudinal study.

Objective: To evaluate elderly patients in a geriatric service, along with their sensory characteristics and their association with clinical aspects.

Methods: This was a descriptive longitudinal study. We enrolled 36 healthy participants of both sexes in this study.

A new biofeedback approach for the control of masseter and temporal myalgia: Utilization of an awake posterior interocclusal device.

: To evaluate the improvement in reducing the pain of patients diagnosed with masticatory myofascial pain and bruxism when undergoing treatment with a partial posterior interocclusal device for the management and control of awake bruxism through biofeedback. : Sixty patients were evaluated during the following periods: pretreatment, 7, 30, and 90 days. The evaluation was carried out by measuring the reduction in pain using clinical and numerical scales.

Pain and temporomandibular disorders in patients with eating disorders.

Orofacial pain and temporomandibular dysfunction may cause chronic facial pain, which may interfere with the emotional state and food intake of patients with eating disorders (ED), such as anorexia nervosa (AN) and bulimia nervosa (BN). Sixty-four patients were assigned to four groups: Group A (AN - restricting subtype): 07; Group B (AN - purging subtype ): 19; Group C (BN): 16; and Group D (control): 22. Complaints of pain are more prevalent in individuals with eating disorders (p<0.

Acupuncture treatment for idiopathic trigeminal neuralgia: A longitudinal case-control double blinded study.

Objective: To evaluate the treatment effect of acupuncture on patients with idiopathic trigeminal neuralgia (ITN) by case-control longitudinal blinded study.

Methods: Sixty ITN patients and 30 healthy subjects were included. The ITN patients were randomly assigned to acupuncture group (15 cases), sham-acupuncture group (15 cases) and carbamazepine group (30 cases), respectively.

Post-operative orofacial pain, temporomandibular dysfunction and trigeminal sensitivity after recent pterional craniotomy: preliminary study.

Background: Surgical trauma at the temporalis muscle is a potential cause of post-craniotomy headache and temporomandibular disorders (TMD). The aim of this study was to evaluate the prevalence of pain, masticatory dysfunction and trigeminal somatosensory abnormalities in patients who acquired aneurysms following pterional craniotomy.

Methods: Fifteen patients were evaluated before and after the surgical procedure by a trained dentist.

Effects of localized versus widespread TMD pain on sleep parameters in patients with bruxism: A single-night polysomnographic study.

Objective: The purpose of this study was to investigate whether the presence of concomitant widespread pain could influence the polysomnographic characteristics of patients with Sleep Bruxism(SB) and chronic masticatory muscle pain(TMD).

Methods: 20 SB/TMD patients (17 women and 3 men) were evaluated according to the RDC/TMD questionnaire; and were divided into two groups according to the absence (Group A) or presence (Group B) of widespread pain. They were evaluated in a one night polysomnography paradigm.

Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters.

Objective: To investigate sexuality and depression in women with FM compared with controls and to correlate the findings with hematological parameters.

Methods: 33 women with FM and 19 healthy women were included and evaluated with the following instruments: Female Sexual Function Index, Beck Inventory, Visual Analogue Scale, medical history and laboratory exams.

Results: The prevalence of sexual dysfunction (P = 0.

Oral Infections and Cytokine Levels in Patients with Alzheimer's Disease and Mild Cognitive Impairment Compared with Controls.

Background: Oral infections are prevalent in the adult population. Their impact includes the implication as a risk factor for Alzheimer's disease (AD), altering its progression. One of the potential mechanisms involves immune mediators such as circulating cytokines.

Temporomandibular disorders in fibromyalgia patients: are there different pain onset?

Objective: To identify temporomandibular disorders (TMD) symptoms in two groups of fibromyalgia patients according to the temporal relation between the onset of facial pain (FP) and generalized body pain (GBP). CROSS-SECTIONAL STUDY DESIGN: Fifty-three consecutive women with fibromyalgia and FP were stratified according to the onset of orofacial pain: Group-A (mean age 47.30 ± 14.

Parafunctional habits are associated cumulatively to painful temporomandibular disorders in adolescents.

This cross-sectional study was designed to evaluate the effect of sleep bruxism, awake bruxism and parafunctional habits, both separately and cumulatively, on the likelihood of adolescents to present painful TMD. The study was conducted on a sample of 1,094 adolescents (aged 12-14). The presence of painful TMD was assessed using the Research Diagnostic Criteria for Temporomandibular Disorders, Axis I.

Periodontitis Response to Anti-TNF Therapy in Ankylosing Spondylitis.

Background: Recently, it has been demonstrated that patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) have a higher risk of periodontitis; however, the effect of anti-TNF therapy in periodontal status of patients with AS and particularly in dental attachment is not known.

Objective: To evaluate longitudinally the local periodontal effect of TNF-antagonist in AS and compare to patients with RA.

Methods: Fifteen patients with AS and 15 RA control patients were prospectively evaluated at baseline and after 6 months (6 M) of anti-TNF therapy.

Chronic pain relief after the exposure of nitrous oxide during dental treatment: longitudinal retrospective study.

The objective was to investigate the effect of nitrous/oxygen in chronic pain. Seventy-seven chronic pain patients referred to dental treatment with conscious sedation with nitrous oxide/oxygen had their records included in this research. Data were collected regarding the location and intensity of pain by the visual analogue scale before and after the treatment.

Sensory abnormalities and masticatory function after microvascular decompression or balloon compression for trigeminal neuralgia compared with carbamazepine and healthy controls.

Object: Idiopathic trigeminal neuralgia (iTN) is a neurological condition treated with pharmacotherapy or neurosurgery. There is a lack of comparative papers regarding the outcomes of neurosurgery in patients with iTN. The objective of this study was to investigate sensory thresholds and masticatory function in 78 patients with iTN who underwent microvascular decompression (MVD) or balloon compression (BC), and compare these treatments with carbamazepine and 30 untreated healthy controls.

Functional and sensory evaluation of patients with idiopathic trigeminal neuralgia: comparison with controls.

Background: Idiopathic trigeminal neuralgia (ITN) can be associated with orofacial and sensory comorbidities.

Objective: To evaluate the masticatory functional and sensory characteristics of patients with ITN compared with controls.

Methods: We enrolled 119 patients and 30 healthy controls.

Evaluation of patients with Alzheimer's disease before and after dental treatment.

Oral infections may play a role in Alzheimer's disease (AD). Objective To describe the orofacial pain, dental characteristics and associated factors in patients with Alzheimer's Disease that underwent dental treatment. Method 29 patients with mild AD diagnosed by a neurologist were included.