Publications by authors named "Jose Rubio Lopez"
Article Synopsis
- Gut bacteria help break down bile acids, which are important for digestion, but how they affect human bile levels is not well understood.
- Scientists studied poop samples from 80 young adults to see how the bacteria in their guts related to bile acid levels in their blood.
- They found that certain types of gut bacteria were linked to higher bile acid levels, showing that our gut health might impact digestion, but more research is needed to be sure.
Circulating bile acids (BA) are signaling molecules that control glucose and lipid metabolism. However, the effects of acute exercise on plasma levels of BA in humans remain poorly understood. Here, we evaluate the effects of a bout of maximal endurance exercise (EE) and resistance exercise (RE) on plasma levels of BA in young, sedentary adults.
View Article and Find Full Text PDFPlasma Levels of Bile Acids Are Related to Cardiometabolic Risk Factors in Young Adults.
J Clin Endocrinol Metab
February 2022
Context: Bile acids (BA) are known for their role in intestinal lipid absorption and can also play a role as signaling molecules to control energy metabolism. Prior evidence suggests that alterations in circulating BA levels and in the pool of circulating BA are linked to an increased risk of obesity and a higher incidence of type 2 diabetes in middle-aged adults.
Objective: We aimed to investigate the association between plasma levels of BA with cardiometabolic risk factors in a cohort of well-phenotyped, relatively healthy young adults.
The congenital dilation of the bile duct is an infrequent pathology in western countries and is associated with the female sex. It is usually diagnosed clinically with complementary tests and evaluated at an early age and also appears frequently in adults. These dilatations are grouped into five types according to Todani's classification, including type Ic (Figure 1).
View Article and Find Full Text PDFAims: The energy expenditure capacity of brown adipose tissue (BAT) makes it an attractive target as a therapy against obesity and type 2 diabetes. BAT activators namely catecholamines, natriuretic peptides and certain myokines, are secreted in response to exercise. ACTIBATE will determine the effect of exercise on BAT activity and mass measured by positron emission tomography/computed tomography (PET/CT, primary outcome) in young adults.
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