Tissue constructs containing mesenchymal stem cells (MSCs) are appealing strategies for repairing large segmental bone defects, but they do not allow consistent bone healing and early cell death was identified as a cause of failure. However, little is known about cell survival in the clinical microenvironment encountered during bone healing process. Osteoconductive coral scaffold with or without luciferase-labeled human MSCs were implanted either in a critical segmental femoral bone defect stabilized by plate or subcutaneously in 44 mice.
View Article and Find Full Text PDFObjective: To report the surgical repair of cor triatriatum sinister (CTS) incorporating heart-beating cardiopulmonary bypass (CPB) in a cat.
Study Design: Clinical case report.
Animal: Fourteen-month-old, 5.
Diagnostic imaging is an important tool to evaluate pancreatic neoplasms. We describe the imaging features of pancreatic malignancies and their benign mimics. Accurate detection and staging are essential for ensuring appropriate selection of patients who will benefit from surgery and for preventing unnecessary surgeries in patients with unresectable disease.
View Article and Find Full Text PDFAm J Vet Res
October 2004
Objective: To quantify radial and longitudinal left ventricular free wall (LVFW) velocities in dogs during the preclinical phase of Golden Retriever muscular dystrophy (GRMD)-associated cardiomyopathy by use of tissue Doppler imaging (TDI).
Animals: 9 dogs with GRMD and 6 healthy control dogs.
Procedure: All dogs (< 3 years old) were examined via conventional echocardiography and 2-dimensional color TDI.
Objective: To report a technique for minimally invasive occlusion of patent ductus arteriosus (PDA) and outcome in 5 dogs.
Study Design: Clinical cases.
Animals: Five, 4-6-month-old, dogs with PDA.