Peritumoral infiltrate in the prognosis of epidermoid carcinoma of the oral cavity.

Introduction: Patients with squamous cell carcinoma of the oral cavity present deficits in their cellular immunity that contribute to neoplastic growth. Thus, the inflammatory activity, such as the immunological response to the tumor, can be used as a prognostic factor.

Objectives: To evaluate the correlation between peritumoral inflammation and clinical characteristics of the patients, survival, and the disease-free interval.

Expression of cancer-testis antigens MAGE-A4 and MAGE-C1 in oral squamous cell carcinoma.

Background: Tumor markers are genes or their products expressed exclusively or preferentially in tumor cells and cancer-testis antigens (CTAs) form a group of genes with a typical expression pattern expressed in a variety of malignant neoplasms. CTAs are considered potential targets for cancer vaccines. It is possible that the CTA MAGE-A4 (melanoma antigen) and MAGE-C1 are expressed in carcinoma of the oral cavity and are related with survival.

Prognostic factors in squamous cell carcinoma of the oral cavity.

Unlabelled: Researchers have been looking for factors that can influence the prognosis of oral cancer, because its outcome is highly uncertain.

Aim: To evaluate variables that can impact the survival rate of patients with squamous-cell carcinoma of the oral cavity.

Material And Methods: Data analysis of 45 patients from January, 2001 to January, 2006.

Mandibular ameloblastoma treated by bone resection and immediate reconstruction.

Multicystic ameloblastoma mainly affects adult patients between the third and seventh decades of life, frequently in the posterior region of the mandible. The resection of a mandible segment without adequate reconstruction produces serious esthetic and functional sequelae leading to a loss of quality of life. The objective of this study is to show that multidisciplinary treatment of ameloblastomas helps in total lesion excision associated with complete reconstruction of the damaged area.